Bratton Laura, Salloum Rabih, Cao Wenqing, Huber Aaron R
Department of Surgical Pathology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 626, Rochester, NY 14642, USA.
Department of Colorectal Surgery, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.
Case Rep Pathol. 2016;2016:4182026. doi: 10.1155/2016/4182026. Epub 2016 Sep 8.
Solitary fibrous tumor is a rare, benign spindle cell neoplasm that was first described in the thoracic pleura. This tumor is now known to occur at many extrapleural sites. There are established criteria for the diagnosis of malignant solitary fibrous tumor including ≥4 mitotic figures per 10 high-power fields, increased cellularity, cytologic atypia, infiltrative margins, and/or necrosis. Although all solitary fibrous tumors have the potential to recur or metastasize, those with malignant histologic features tend to behave more aggressively. We report a case of solitary fibrous tumor, with malignant histologic features, in a 21-year-old woman which arose from the serosal surface of the sigmoid colon.
孤立性纤维瘤是一种罕见的良性梭形细胞瘤，最初在胸膜中被描述。现在已知这种肿瘤可发生于许多胸膜外部位。对于恶性孤立性纤维瘤的诊断有既定标准，包括每10个高倍视野中≥4个有丝分裂象、细胞增多、细胞异型性、浸润性边缘和/或坏死。尽管所有孤立性纤维瘤都有复发或转移的可能，但具有恶性组织学特征的肿瘤往往行为更具侵袭性。我们报告一例发生于一名21岁女性乙状结肠浆膜面的具有恶性组织学特征的孤立性纤维瘤病例。
