Wallace Sean J, Teixeira Robert, Miller Nathan F, Raj Mamtha, Sheikh Hina, Sharma Rohit
Division of Plastic & Reconstructive Surgery, Department of Surgery, Lehigh Valley Health Network, Allentown, Pa.
Division of Dermatopathology, Department of Pathology, Health Network Laboratories, Allentown, Pa.
Eplasty. 2018 Oct 11;18:e31. eCollection 2018.
: Mesenchymal in origin, solitary fibrous tumors are primarily seen within the pleura of the lung or in serosal-lined body cavities. Constituting 1% to 2% of all soft-tissue tumors, solitary fibrous tumors are rare entities, especially when found in extrapleural and in superficial locations. A review of literature for superficial solitary fibrous tumors revealed 71 reports in case reports and small case series. : In this report, we describe a 74-year-old man with an extrapleural superficial solitary fibrous tumor, as well as present a review of the current published literature to date. : We present the clinical course, surgical procedure, histopathological features, and treatment options, as well as present a compilation of the published data on superficial solitary fibrous tumors. : Based on the current literature, solitary fibrous tumors are more common in middle-aged women and in the head and neck region. Diagnosis of solitary fibrous tumors requires tissue sampling and staining for immunohistochemical markers. Management of these tumors is based on wide local excision with histologically negative margins. If negative margins cannot be surgically achieved, adjuvant therapies including radiation have been described. With extrapleural manifestations of solitary fibrous tumors seldom reported in the literature, it is our hope that reporting these unusual instances will raise awareness of such disease manifestations and allow for earlier diagnosis and treatment.
孤立性纤维瘤起源于间充质，主要见于肺胸膜或浆膜衬里的体腔。孤立性纤维瘤占所有软组织肿瘤的1%至2%，是罕见的实体瘤，尤其是在胸膜外和浅表部位发现时。对浅表孤立性纤维瘤的文献回顾显示，病例报告和小病例系列中有71篇报道。：在本报告中，我们描述了一名患有胸膜外浅表孤立性纤维瘤的74岁男性，并对目前已发表的文献进行了综述。：我们介绍了临床过程、手术步骤、组织病理学特征和治疗选择，并汇总了已发表的关于浅表孤立性纤维瘤的数据。：根据目前的文献，孤立性纤维瘤在中年女性和头颈部区域更为常见。孤立性纤维瘤的诊断需要组织取样和免疫组化标记物染色。这些肿瘤的治疗基于广泛的局部切除，切缘组织学阴性。如果手术无法实现阴性切缘，则已描述了包括放疗在内的辅助治疗。由于文献中很少报道孤立性纤维瘤的胸膜外表现，我们希望报告这些不寻常的病例能够提高对这种疾病表现的认识，并实现早期诊断和治疗。
