年轻男男性行为人群的肛门鳞状上皮内病变与 HPV 感染
Anal Squamous Intraepithelial Lesions and HPV Among Young Black Men Who Have Sex with Men.
机构信息
1 Primary Care Department, Howard Brown Health , Chicago, Illinois.
2 Department of Medicine, University of Chicago , Chicago, Illinois.
出版信息
LGBT Health. 2017 Feb;4(1):72-74. doi: 10.1089/lgbt.2016.0049. Epub 2016 Sep 27.
PURPOSE
Limited data are available on anal squamous intraepithelial lesions (ASILs) and anal human papillomavirus (HPV) infection in young, Black populations. The purpose of this study was to examine the prevalence of and relationships between ASILs and high-risk HPV infection in a young (<30 years of age), predominantly Black, men who have sex with men (MSM) population.
METHODS
Results of anal cytology and HPV DNA were gathered for 83 individuals.
RESULTS
Forty-two percent of individuals (35) had atypical squamous cells of undetermined significance and 33% (27) had low-grade squamous intraepithelial lesion by cytology. Only 9% tested positive for both high-risk HPV subtypes 16 and 18.
CONCLUSION
Low rates of infection with both HPV types 16 and 18 may provide further evidence that we should continue to vaccinate young, Black MSM against HPV.
目的
关于年轻的黑人人群中的肛门鳞状上皮内病变（ASIL）和肛门人乳头瘤病毒（HPV）感染，目前数据有限。本研究的目的是在一个年轻（<30 岁）、主要为黑人、男男性行为者（MSM）人群中，调查 ASIL 和高危 HPV 感染的流行率和相关性。
方法
对 83 个人的肛门细胞学和 HPV DNA 结果进行了收集。
结果
42%的人（35 人）的细胞学检查结果为非典型鳞状细胞不能明确意义，33%（27 人）为低级别鳞状上皮内病变。只有 9%的人同时检测到高危 HPV 亚型 16 和 18 呈阳性。
结论
HPV 类型 16 和 18 的感染率较低，这可能进一步证明我们应该继续为年轻的黑人 MSM 接种 HPV 疫苗。
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