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超声引导下枕大神经中间部位浸润:一项技术可行性研究。

Ultrasound-Guided Intermediate Site Greater Occipital Nerve Infiltration: A Technical Feasibility Study.

作者信息

Zipfel Jonathan, Kastler Adrian, Tatu Laurent, Behr Julien, Kechidi Rachid, Kastler Bruno

机构信息

Radiology Unit, CIMVES Vesoul, France.

Neuroradiology and MRI unit, Grenoble University Hospital, France; University of Grenoble Alpes, Grenoble Institute des Neurosciences, Inserm, U1216, Grenoble, France.

出版信息

Pain Physician. 2016 Sep-Oct;19(7):E1027-34.

Abstract

BACKGROUND

Two studies recently reported that computed tomography (CT) guided infiltration of the greater occipital nerve at its intermediate site allows a high efficacy rate with long-lasting pain relief following procedure in occipital neuralgia and in various craniofacial pain syndromes.

OBJECTIVE

The purpose of our study was to evaluate the technical feasibility and safety of ultrasound-guided intermediate site greater occipital nerve infiltration.

STUDY DESIGN

Retrospective study.

SETTING

This study was conducted at the imaging department of a 1,409 bed university hospital.

METHODS

Local institutional review board approval was obtained and written consent was waived. In this retrospective study, 12 patients suffering from refractory occipital neuralgia or craniofacial pain syndromes were included between April and October 2014. They underwent a total of 21 ultrasound-guided infiltrations. Infiltration of the greater occipital nerve was performed at the intermediate site of the greater occipital nerve, at its first bend between obliqus capitis inferior and semispinalis capitis muscles with local anestetics and cortivazol. Technical success was defined as satisfactory diffusion of added iodinated contrast media in the fatty space between these muscles depicted on control CT scan. We also reported first data of immediate block test efficacy and initial clinical efficacy at 7 days, one month, and 3 months, defined by a decrease of at least 50% of visual analog scale (VAS) scores.

RESULTS

Technical success rate was 95.24%. Patients suffered from right unilateral occipital neuralgia in 3 cases, left unilateral occipital neuralgia in 2 cases, bilateral occipital neuralgia in 2 cases, migraine in one case, cervicogenic headache in one case, tension-type headache in 2 cases, and cluster headache in one case. Block test efficacy was found in 93.3% (14/15) cases. Clinical efficacy was found in 80% of cases at 7 days, in 66.7% of cases at one month and in 60% of cases at 3 months. No major complications were noted.

LIMITATIONS

Some of the limitations of our study include that it represents a single institution. The low number of infiltrations included in this study, for this guidance procedure, is another bias.

CONCLUSIONS

This ultrasound-guided infiltration technique appears to be feasible, safe, non-ionizing, and fast when targeting the greater occipital nerve in its intermediate portion. This imaging guidance modality should be used in routine clinical practice.

KEY WORDS

Greater occipital nerve, infiltration, ultrasound guidance, corticosteroids, occipital neuralgia, craniofacial pain syndrome.

摘要

背景

最近两项研究报告称,计算机断层扫描(CT)引导下在枕大神经中间部位进行浸润,对于枕神经痛和各种颅面部疼痛综合征患者,术后能实现较高的有效率和持久的疼痛缓解。

目的

本研究旨在评估超声引导下枕大神经中间部位浸润的技术可行性和安全性。

研究设计

回顾性研究。

研究地点

本研究在一家拥有1409张床位的大学医院的影像科进行。

方法

获得了当地机构审查委员会的批准,并免除了书面同意书。在这项回顾性研究中,纳入了2014年4月至10月期间12例患有难治性枕神经痛或颅面部疼痛综合征的患者。他们总共接受了21次超声引导下的浸润操作。在枕大神经的中间部位,即在头下斜肌和头半棘肌之间的第一个弯曲处进行枕大神经的浸润,并注入局部麻醉剂和皮质类固醇。技术成功的定义为,在对照CT扫描上显示,添加的碘化造影剂在这些肌肉之间的脂肪间隙中扩散良好。我们还报告了即时阻滞试验疗效以及在7天、1个月和3个月时的初始临床疗效的首批数据,疗效定义为视觉模拟量表(VAS)评分至少降低50%。

结果

技术成功率为95.24%。3例患者患有右侧单侧枕神经痛,2例患有左侧单侧枕神经痛,2例患有双侧枕神经痛,1例患有偏头痛,1例患有颈源性头痛,2例患有紧张型头痛,1例患有丛集性头痛。阻滞试验有效率为93.3%(14/15)。7天时80%的病例有临床疗效,1个月时66.7%的病例有临床疗效,3个月时60%的病例有临床疗效。未发现重大并发症。

局限性

本研究的一些局限性包括它是单中心研究。本研究纳入的用于该引导操作的浸润次数较少,这是另一个偏倚。

结论

当针对枕大神经的中间部分时,这种超声引导下的浸润技术似乎是可行、安全、非电离且快速的。这种影像引导方式应在常规临床实践中使用。

关键词

枕大神经;浸润;超声引导;皮质类固醇;枕神经痛;颅面部疼痛综合征

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