de Graaff J, van Winkelhoff A J, Goené R J
Department of Oral Microbiology, Academic Centre for Dentistry (ACTA), Amsterdam.
Infection. 1989 Jul-Aug;17(4):269-71. doi: 10.1007/BF01639538.
The different forms of periodontitis are all associated with a distinct bacterial flora. However, a clear relationship is described between localized juvenile periodontitis (LJP) and Actinobacillus actinomycetemcomitans. Eleven LJP patients all harboured A. actinomycetemcomitans. The arrest of LJP is often impossible, due to the inability to eliminate A. actinomycetemcomitans. Therefore, antibiotic treatment was introduced in combination with the initial treatment. We studied the effect of periodontal treatment on the microflora and clinical status of periodontal disease patients using different therapies. Group 3 attained the best results (initial treatment and a combination metronidazole and amoxicillin), the group to eliminate A. actinomycetemcomitans effectively.
不同形式的牙周炎均与独特的细菌菌群相关。然而，局限性青少年牙周炎（LJP）与伴放线放线杆菌之间存在明确的关系。11例LJP患者均携带伴放线放线杆菌。由于无法清除伴放线放线杆菌，LJP的病情往往难以得到控制。因此，在初始治疗的基础上引入了抗生素治疗。我们采用不同疗法研究了牙周治疗对牙周病患者微生物菌群及临床状况的影响。第3组取得了最佳效果（初始治疗加甲硝唑与阿莫西林联合使用），该组能有效清除伴放线放线杆菌。
