Haslam Alyson, Wirth Michael D, Robb Sara Wagner
College of Public Health, Department of Epidemiology and Biostatistics, University of Georgia, Athens, GA, USA.
Cancer Prevention and Control Program and Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Stress Health. 2017 Aug;33(3):298-306. doi: 10.1002/smi.2706. Epub 2016 Sep 28.
The purpose of this study was to characterize sympathetic activity by using waking salivary alpha-amylase (sAA) concentrations in a group of long-term meditation instructors and to examine the association between meditation (depth, dose and duration) and the waking alpha-amylase response. Salivary alpha-amylase samples were collected (immediately upon waking and at 15-min, 30-min and 45-min intervals after waking) from mindfulness-based stress reduction instructors to determine both the area under the curve and the awakening slope (difference in alpha-amylase concentrations between waking and 30-min post-waking). It was determined through general linear models that neither years of meditation nor meditation dose were associated with the awakening sAA slope, but higher scores for meditation depth (greater depth) was associated with a more negative (or steeper) awakening slope [Quartile (Q)1: -7 versus Q4: -21 U/mL; p = 0.06], in fully adjusted models. Older age (p = 0.04) and a later time of waking (p < 0.01) also were associated with less negative awakening slope values. Smoking was associated with lower area under the curve values (smokers: 1716 U/mL versus nonsmokers: 2107 U/mL; p = 0.05) in fully adjusted models. The results suggest a 'healthy' sAA waking slope among individuals who meditate more deeply. Copyright © 2016 John Wiley & Sons, Ltd.
本研究的目的是通过测量一组长期冥想导师清醒时的唾液α-淀粉酶（sAA）浓度来表征交感神经活动，并研究冥想（深度、剂量和持续时间）与清醒时α-淀粉酶反应之间的关联。从正念减压疗法导师那里收集唾液α-淀粉酶样本（醒来后立即以及醒来后15分钟、30分钟和45分钟时），以确定曲线下面积和觉醒斜率（醒来时与醒来后30分钟时α-淀粉酶浓度的差值）。通过一般线性模型确定，冥想年限和冥想剂量均与觉醒sAA斜率无关，但在完全调整模型中，冥想深度得分较高（深度更大）与更负（或更陡）的觉醒斜率相关[四分位数（Q）1：-7与Q4：-21 U/mL；p = 0.06]。年龄较大（p = 0.04）和醒来时间较晚（p < 0.01）也与较不负面的觉醒斜率值相关。在完全调整模型中，吸烟与曲线下面积值较低相关（吸烟者：1716 U/mL与非吸烟者：2107 U/mL；p = 0.05）。结果表明，冥想更深的个体具有“健康的”sAA觉醒斜率。版权所有© 2016约翰威立父子有限公司。
