Oral findings in the autoimmune polyendocrinopathy-candidosis syndrome (APECS) and other forms of hypoparathyroidism.

Of twenty-eight patients aged 4 to 28 years with the autoimmune polyendocrinopathy-candidosis syndrome (APECS), twenty-seven had chronic oral candidosis, twenty-five had HPT, twenty-three had enamel hypoplasia, and nineteen had hypoadrenocorticism. Of three patients with other forms of hypoparathyroidism, none had any associated disease or oral abnormality. In nineteen cases candidosis was the first manifestation of APECS. Its occurrence was independent of the other components of the syndrome. The occurrence of enamel hypoplasia also was independent of HPT. Possibly, the enamel organ was affected by an autoimmune episode. No delayed maturation, resorption, or root hypoplasia was observed. Tooth impaction occurred in three patients.