Olekszyk J, Siliunas V, Mauer T, Biondi R
J Am Osteopath Assoc. 1989 Jul;89(7):901-4.
We report a case of fibrosarcoma of the nose and paranasal sinuses and give a brief review of the literature. Fibrosarcoma of the nose and paranasal sinuses is uncommon, and few cases have been reported to date. Previously these tumors may have been overdiagnosed secondary to inadequate diagnostic procedures. Because histologic diagnosis is difficult, these tumors have been confused with other lesions of the head and neck. Thus, the improvement in diagnostic procedures has significantly reduced the reported incidence of fibrosarcoma. Because histologic diagnosis is difficult, this tumor has often been confused with other lesions of the head and neck. To ensure proper handling of the tissue, the pathologist should be informed if fibrosarcoma is suspected. It may be necessary to use electron microscopy or staining techniques such as immunoperoxidase stains to distinguish fibrosarcoma from other lesions. Unfortunately, the early signs and symptoms of the tumor are vague and sometimes misleading. Thus, at the patient's initial visit, it is important that the physician consider the possibility of fibrosarcoma.
我们报告了一例鼻及鼻窦纤维肉瘤病例，并对相关文献进行简要综述。鼻及鼻窦纤维肉瘤并不常见，迄今为止报道的病例较少。以前，由于诊断程序不完善，这些肿瘤可能被过度诊断。由于组织学诊断困难，这些肿瘤曾与头颈部的其他病变相混淆。因此，诊断程序的改进显著降低了纤维肉瘤的报告发病率。由于组织学诊断困难，这种肿瘤常与头颈部的其他病变相混淆。为确保对组织进行妥善处理，若怀疑为纤维肉瘤，应告知病理学家。可能需要使用电子显微镜或免疫过氧化物酶染色等染色技术来区分纤维肉瘤与其他病变。不幸的是，该肿瘤的早期体征和症状不明确，有时具有误导性。因此，在患者初诊时，医生考虑纤维肉瘤的可能性很重要。
