Jamshidi Khodamorad, Najd-Mazhar Farid, Abolghasemzadeh Ahangar Farshad, Mirzaei Alireza
Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran.
Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran.
J Orthop Sci. 2017 Jan;22(1):69-74. doi: 10.1016/j.jos.2016.09.002. Epub 2016 Sep 25.
Limb salvage following the resection of tumor from the proximal part of the humerus, poses many challenges, and there is no consensus regarding the best reconstructive technique after proximal humerus resection. The aim of this study was to evaluate the effect of anteromedial placing of the plate in the absence of deltoid muscle and cement augmentation on the functional outcome, complication rate and survival of proximal humerus allograft reconstruction.
A number of 36 osteoarticular allograft reconstructions of proximal humerus were included in final study. In 26 cases, medullary canal of the allograft was filled by cement and the complication rate and survival was compared to non-cemented allografts. In addition, anteromedial placement of plate was applied for all resection type IB (18 cases), in which the deltoid muscle was resected. The mean follow-up of patients was 46 months.
In total, 12 complications including 3 fractures, 4 resorptions, 3 infections and 2 nonunions were reported. Complication rates were significantly lower in cemented allografts (p = 0.001). Five year survival rates of cemented and non-cemented allografts were found to be 82% and 70%, respectively. The mean MSTS score was 84.9%, ranging 76-90.
According to our results, cement augmentation improves survival and reduces the complication rate of allografts. Moreover, our results showed that anteromedial placing of the plate in resection type IB could improve the functional outcome of allografts. However, the detailed effect of anteromedial plating should be further investigated in future studies.
肱骨近端肿瘤切除后的保肢手术面临诸多挑战,对于肱骨近端切除术后的最佳重建技术尚无共识。本研究的目的是评估在无三角肌及骨水泥增强的情况下,钢板置于肱骨近端前内侧对同种异体骨重建的功能结果、并发症发生率及生存率的影响。
最终纳入36例肱骨近端骨关节同种异体骨重建病例。其中26例同种异体骨的髓腔用骨水泥填充,并将其并发症发生率及生存率与未用骨水泥的同种异体骨进行比较。此外,对于所有IB型切除(18例)且三角肌被切除的病例,钢板均置于肱骨近端前内侧。患者的平均随访时间为46个月。
共报告12例并发症,包括3例骨折、4例吸收、3例感染和2例骨不连。骨水泥增强的同种异体骨并发症发生率显著更低(p = 0.001)。骨水泥增强和未增强的同种异体骨的5年生存率分别为82%和70%。平均肌肉骨骼肿瘤学会(MSTS)评分为84.9%,范围在76 - 90之间。
根据我们的结果,骨水泥增强可提高同种异体骨的生存率并降低并发症发生率。此外,我们的结果表明,在IB型切除中钢板置于肱骨近端前内侧可改善同种异体骨的功能结果。然而,钢板置于肱骨近端前内侧的具体效果有待未来研究进一步探讨。