Gupta S, Kafchinski L A, Gundle K R, Saidi K, Griffin A M, Wunder J S, Ferguson P C
Glasgow Royal Infirmary, 84 Castle St, Glasgow G4 0SF, UK.
Texas Tech University Health Sciences Center El Paso, 4801 Alberta Avenue El Paso, TX 79905, USA.
Bone Joint J. 2017 Jul;99-B(7):973-978. doi: 10.1302/0301-620X.99B7.BJJ-2016-0996.
Intercalary allografts following resection of a primary diaphyseal tumour have high rates of complications and failures. At our institution intercalary allografts are augmented with intramedullary cement and fixed using compression plating. Our aim was to evaluate their long-term outcomes.
A total of 46 patients underwent reconstruction with an intercalary allograft between 1989 and 2014. The patients had a mean age of 32.8 years (14 to 77). The most common diagnoses were osteosarcoma (n = 16) and chondrosarcoma (n = 9). The location of the tumours was in the femur in 21, the tibia in 16 and the humerus in nine. Function was assessed using the Musculoskeletal Tumor Society (MSTS) scoring system and the Toronto Extremity Salvage Score (TESS). The survival of the graft and the overall survival were assessed using the Kaplan-Meier method.
The median follow-up was 92 months (4 to 288). The mean MSTS 87 score was 29.1 (19 to 35), the mean MSTS 93 score was 82.2 (50 to 100) and the mean TESS score was 81.2 (43 to 100). Overall survival of the allograft was 84.8%. A total of 15 patients (33%) had a complication. Five allografts were revised for complications and one for local recurrence.
Intercalary allografts augmented with intramedullary cement and compression plate fixation provide a reliable and durable method of reconstruction after the excision of a primary diaphyseal bone tumour, with high levels of function and satisfaction. Cite this article: 2017;99-B:973-8.
原发性骨干肿瘤切除术后采用间置同种异体骨移植,并发症和失败率较高。在我们机构,间置同种异体骨移植采用髓内骨水泥增强并使用加压钢板固定。我们的目的是评估其长期疗效。
1989年至2014年间,共有46例患者接受了间置同种异体骨移植重建。患者的平均年龄为32.8岁(14至77岁)。最常见的诊断为骨肉瘤(n = 16)和软骨肉瘤(n = 9)。肿瘤位于股骨21例,胫骨16例,肱骨9例。使用肌肉骨骼肿瘤学会(MSTS)评分系统和多伦多肢体挽救评分(TESS)评估功能。采用Kaplan-Meier法评估移植骨的存活率和总生存率。
中位随访时间为92个月(4至288个月)。MSTS 87评分的平均值为29.1(19至35),MSTS 93评分的平均值为82.2(50至100),TESS评分的平均值为81.2(43至100)。移植骨的总生存率为84.8%。共有15例患者(33%)出现并发症。5例同种异体骨因并发症进行了翻修,1例因局部复发进行了翻修。
髓内骨水泥增强和加压钢板固定的间置同种异体骨移植为原发性骨干骨肿瘤切除术后提供了一种可靠且持久的重建方法,功能水平和满意度较高。引用本文:2017;99-B:973-8。