Mechsner S
Klinik für Gynäkologie, Endometriosezentrum Charité, Charité - Universitätsmedizin Berlin, Hindenburgdamm 30, 12200, Berlin, Deutschland.
Schmerz. 2016 Oct;30(5):477-490. doi: 10.1007/s00482-016-0154-1.
Endometriosis is a chronic disease of women during their reproductive age. The most typical symptoms are dysmenorrhoea, dyspareunia, dysuria, cyclical and acyclical pelvic pain, bleeding disorders and infertility. These symptoms lead to significant impairment of the quality of life and economic burden. The prevalence is estimated to be 2-20 % of all women in this age and due to this fact, it is one of the most frequently benign gynecological diseases. Not all women suffer from severe symptoms, but more than 50 % require ongoing treatment. Beside the severe physical impairment due to the pain, the high recurrence rate of 50-80 % also after surgical and/or hormonal treatment is problematic. The interval between onset of symptoms and diagnosis is approximately 6-8 years. These problems are a consequence of lack of knowledge about the pathogenesis of the disease and the pain mechanisms as well as the lack of awareness of physicians in this field.
子宫内膜异位症是育龄期女性的一种慢性疾病。最典型的症状是痛经、性交困难、排尿困难、周期性和非周期性盆腔疼痛、出血紊乱以及不孕。这些症状会导致生活质量严重受损和经济负担加重。据估计,该病在这个年龄段的所有女性中的患病率为2%至20%,正因为如此,它是最常见的良性妇科疾病之一。并非所有女性都会出现严重症状,但超过50%的患者需要持续治疗。除了疼痛导致的严重身体损伤外,手术和/或激素治疗后50%至80%的高复发率也是个问题。症状出现与诊断之间的间隔约为6至8年。这些问题是由于对该疾病的发病机制和疼痛机制缺乏了解,以及该领域医生缺乏认识所致。