Norhagen G, Engström P E, Hammarström L, Söder P O, Smith C I
Department of Clinical Immunology, Karolinska Institute, Huddinge Hospital, Stockholm, Sweden.
J Clin Immunol. 1989 Jul;9(4):279-86. doi: 10.1007/BF00918659.
Total levels of IgA, IgM, and IgG were measured in unstimulated whole saliva and serum from 63 individuals with selective IgA deficiency. Values were compared with the incidence of upper respiratory tract infections, antibiotic treatments (necessitated by upper respiratory tract infection), and HLA antigens. A statistically significant increase in salivary IgM and IgG levels was noted in individuals with selective IgA deficiency compared to healthy normal individuals. Healthy individuals with selective IgA deficiency did not have increased concentrations of salivary IgM compared to infectious-prone patients. Nor was there any correlation found between proneness to infections and HLA antigens or between salivary IgM or IgG levels and HLA antigens in this patient material.
对63例选择性IgA缺乏症患者未刺激的全唾液和血清中的IgA、IgM和IgG总水平进行了测量。将这些值与上呼吸道感染的发生率、抗生素治疗（因上呼吸道感染而必需）以及HLA抗原进行比较。与健康正常个体相比，选择性IgA缺乏症患者的唾液IgM和IgG水平有统计学意义的升高。与易感染患者相比，选择性IgA缺乏症的健康个体唾液IgM浓度并未升高。在该患者群体中，感染倾向与HLA抗原之间、唾液IgM或IgG水平与HLA抗原之间均未发现任何相关性。
