Santos João Vasco, Lisboa Carmen, Lanna Caterina, Costa-Pereira Altamiro, Freitas Alberto
Department of Health Information and Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.
Dermatology. 2016;232(5):613-618. doi: 10.1159/000448515. Epub 2016 Sep 30.
BACKGROUND/AIMS: Hidradenitis suppurativa (HS), a chronic inflammatory skin disease of the hair follicle, can lead to scarring and disability. With an estimated European prevalence of 1%, few epidemiological studies of HS have been performed, and none focused on hospitalisations. We aimed to study the time trends of HS hospitalisations and to evaluate the demographic characteristics, hospital incidence rate, readmissions, length of stay, comorbidities and risk factors of hospitalised HS patients.
We performed a retrospective observational study using a national administrative database in Portugal, with discharges between 2000 and 2014. All the inpatients aged 5 years or more with a diagnosis of HS were included. Variables analysed were age, sex, admission and discharge date, discharge outcome and diagnoses.
A total of 1,177 patients were hospitalised in this time period (48 were aged 18 years or younger) with a male-to-female ratio of 1:1.17. There was a hospital incidence rate of 0.83 patients with HS per 100,000 person-years (95% CI = 0.78-0.88). The age group with the highest incidence rate was 20-29 years among women and 40-49 years among men. We recorded an increasing trend in the number of new hospitalised patients and in the hospital incidence rate of HS. Tobacco was the most common comorbidity/risk factor. Eighty-three percent of our population underwent HS surgery.
This hospital-based incidence study showed that admission for HS is increasing and that the majority of the HS inpatients were surgical cases. In the future, prospective studies will be important to assess risk factors for hospitalisations and complications.
背景/目的：化脓性汗腺炎（HS）是一种毛囊慢性炎症性皮肤病，可导致瘢痕形成和残疾。据估计，HS在欧洲的患病率为1%，但针对HS的流行病学研究较少，且均未聚焦于住院情况。我们旨在研究HS住院的时间趋势，并评估HS住院患者的人口统计学特征、医院发病率、再入院情况、住院时间、合并症及危险因素。
我们利用葡萄牙的一个国家行政数据库进行了一项回顾性观察研究，纳入2000年至2014年期间的出院病例。纳入所有年龄在5岁及以上且诊断为HS的住院患者。分析的变量包括年龄、性别、入院和出院日期、出院结局及诊断。
在此期间，共有1177例患者住院（48例年龄在18岁及以下），男女比例为1:1.17。HS的医院发病率为每10万人年0.83例患者（95%置信区间=0.78-0.88）。发病率最高的年龄组在女性中为20-29岁，在男性中为40-49岁。我们记录到新住院患者数量及HS医院发病率呈上升趋势。烟草是最常见的合并症/危险因素。我们研究中的83%的患者接受了HS手术。
这项基于医院的发病率研究表明，HS的住院人数在增加，且大多数HS住院患者为手术病例。未来，前瞻性研究对于评估住院及并发症的危险因素将很重要。
