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Focus on adequate antimicrobial treatment and de-escalation in the ICU.

作者信息

Benoit Dominique D, Doig Gordon, Timsit Jean-Francois

机构信息

Department of Intensive Care, Ghent University Hospital, Ghent, Belgium.

Northern Clinical School Intensive Care Research Unit, University of Sydney, Sydney, 2006, Australia.

出版信息

Intensive Care Med. 2016 Dec;42(12):1856-1858. doi: 10.1007/s00134-016-4566-2. Epub 2016 Sep 29.

DOI:10.1007/s00134-016-4566-2
PMID:27686358
Abstract
摘要

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Strategies to reduce curative antibiotic therapy in intensive care units (adult and paediatric).在重症监护病房（成人和儿科）减少有治疗作用的抗生素治疗的策略。
Intensive Care Med. 2015 Jul;41(7):1181-96. doi: 10.1007/s00134-015-3853-7. Epub 2015 Jun 3.
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Preventive and therapeutic strategies in critically ill patients with highly resistant bacteria.
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Intensive Care Med. 2015 May;41(5):776-95. doi: 10.1007/s00134-015-3719-z. Epub 2015 Mar 20.
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Ten tips on how to win the war against resistance to antibiotics.关于如何打赢抗抗生素耐药性之战的十条建议。
Intensive Care Med. 2015 May;41(5):899-901. doi: 10.1007/s00134-014-3594-z. Epub 2015 Jan 9.
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Linezolid plasma and intrapulmonary concentrations in critically ill obese patients with ventilator-associated pneumonia: intermittent vs continuous administration.危重症肥胖患者呼吸机相关性肺炎中利奈唑胺的血药浓度和肺组织浓度：间断给药与持续给药的比较。
Intensive Care Med. 2015 Jan;41(1):103-10. doi: 10.1007/s00134-014-3550-y. Epub 2014 Nov 21.
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De-escalation versus continuation of empirical antimicrobial treatment in severe sepsis: a multicenter non-blinded randomized noninferiority trial.严重脓毒症中经验性抗菌治疗的降级与持续治疗：一项多中心非盲随机非劣效性试验。
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