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溃疡分枝杆菌信州亚种的全基因组序列

Complete Genome Sequence of Mycobacterium ulcerans subsp. shinshuense.

作者信息

Yoshida Mitsunori, Nakanaga Kazue, Ogura Yoshitoshi, Toyoda Atsushi, Ooka Tadasuke, Kazumi Yuko, Mitarai Satoshi, Ishii Norihisa, Hayashi Tetsuya, Hoshino Yoshihiko

机构信息

Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, Higashi-Murayama, Tokyo, Japan.

Department of Bacteriology, Faculty of Medicine Sciences, Kyushu University, Fukuoka, Fukuoka, Japan.

出版信息

Genome Announc. 2016 Sep 29;4(5):e01050-16. doi: 10.1128/genomeA.01050-16.

Abstract

Mycobacterium ulcerans subsp. shinshuense produces mycolactone and causes Buruli ulcer. Here, we report the complete sequence of its genome, which comprises a 5.9-Mb chromosome and a 166-kb plasmid (pShT-P). The sequence will represent the essential data for future phylogenetic and comparative genome studies of mycolactone-producing mycobacteria.

摘要

溃疡分枝杆菌信州亚种产生分枝杆菌内酯并引发布鲁里溃疡。在此,我们报告其基因组的完整序列,该序列由一条590kb的染色体和一个166kb的质粒(pShT-P)组成。该序列将为未来产分枝杆菌内酯分枝杆菌的系统发育和比较基因组研究提供重要数据。

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