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被抗生素耐药菌定植的患者——医疗病房中感染的一个潜在来源。

Patients colonized by antibiotic resistant bacteria--a potential source of infections in the medical wards.

作者信息

Danchaivijitr S, Trakulsomboon S

出版信息

J Med Assoc Thai. 1989 Jul;72 Suppl 2:33-8.

PMID:2769130
Abstract

Bacterial colonization was studied in 12 non-infected female patients admitted into one medical ward, Siriraj hospital, Bangkok, from March to June 1988. Swabs were taken on the first day of admission, then every other day until discharge, from six sites; i.e. anterior nares, vault of axilla, hands, anterior chest, abdomen and toe web. The times and total number of swabbing were 52 and 312 respectively. All patients were colonized with bacteria. S. epidermidis was found in all patients. S. aureus was found in 9 patients, 48 times (15.4%). Methicillin-resistant S. aureus (M.R.S.A.) was identified in 4 patients on 10 occasions (3.2%). Gram-negative bacilli were isolated in 11 of 12 patients, and the number of positive samples was 60 (19.2%). All bacteria were highly resistant to the commonly used antimicrobials. The study failed to show that colonization increased with the duration of hospitalization. It is concluded that the majority of patients who had been colonized with pathogenic bacteria were important sources of infections in the medical ward.

摘要

1988年3月至6月期间,对曼谷诗里拉吉医院一个内科病房收治的12名未感染的女性患者进行了细菌定植研究。入院第一天采集拭子样本,之后每隔一天采集一次,直至出院,采集部位有六个,即双侧前鼻孔、双侧腋窝、双手、前胸、腹部和双侧趾间。采样次数和采样总数分别为52次和312次。所有患者均有细菌定植。所有患者均检出表皮葡萄球菌。9名患者检出金黄色葡萄球菌,共48次(15.4%)。4名患者10次检出耐甲氧西林金黄色葡萄球菌(MRSA,3.2%)。12名患者中有11名分离出革兰氏阴性杆菌,阳性样本数为60次(19.2%)。所有细菌对常用抗菌药物均具有高度耐药性。该研究未能表明定植率随住院时间延长而增加。研究得出结论,大多数定植病原菌的患者是内科病房感染的重要来源。

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