Anneroth G, Eneroth C M, Isacsson G, Lundquist P G
Scand J Dent Res. 1978 May;86(3):182-92. doi: 10.1111/j.1600-0722.1978.tb01930.x.
Twenty-one submandibular salivary calculi from 19 patients were examined with the light and electron microscope. Adjacent to the peripheral parts of the calculi metaplastic squamous epithelium or connective tissue was seen in close contact to the mineralized matrix. Disintegrated cellular substances from these tissue components were in some cases found to condense in a peripherally located zone of the salivary calculi. The morphology of the examined salivary calculi varied extensively not only within each calculus but also from one calculus to another. High and low incidence of crystals gave rise to the lamellated pattern. In some cases the crystals were so abundant as to five a dense homogeneous appearance. In the central parts of the calculi spheroid bodies of very low electron density with a size ranging from 1 to 100micrometer were found in an amorphous matrix. The origin of these structures is discussed. In the peripheral parts of some calculi osmiophilic spherical bodies with an electron microscopical appearance similar to lipid granules as well as bacteria of cocci or coliform type were found. Degenerated bacteria might in some cases contribute in forming part of the peripheral organic matrix.
对来自19名患者的21颗下颌下涎腺结石进行了光镜和电镜检查。在结石的周边部分附近，可见化生的鳞状上皮或结缔组织与矿化基质紧密接触。在某些情况下，发现这些组织成分的崩解细胞物质在涎腺结石的周边区域浓缩。所检查的涎腺结石的形态不仅在每个结石内部变化很大，而且在不同结石之间也有很大差异。晶体的高发生率和低发生率产生了层状模式。在某些情况下，晶体非常丰富，呈现出致密均匀的外观。在结石的中心部分，在无定形基质中发现了电子密度极低、大小从1到100微米不等的球状体。讨论了这些结构的起源。在一些结石的周边部分，发现了嗜锇性球状体，其电子显微镜外观类似于脂质颗粒，以及球菌或大肠菌类型的细菌。在某些情况下，退化的细菌可能有助于形成周边有机基质的一部分。
