Fillyaw M J, Badger G J, Bradley W G, Tandan R, Blair C J, Fries T J, Wilder D G, Boerman J, Young J, Witarsa M
Department of Neurology, University of Vermont, Burlington 05405.
J Neurol Sci. 1989 Aug;92(1):17-36. doi: 10.1016/0022-510x(89)90172-x.
Interexaminer and intraexaminer reliability were determined for 30 quantitative measures of neurological function, including sensory threshold, tendon reflexes, maximum isometric strength, and timed tests and coded ratings of functional ability, in patients with Charcot-Marie-Tooth disease (n = 30), idiopathic polyneuropathy (n = 16) and spinocerebellar degeneration (n = 30). Five of 6 sensory and reflex measures had interexaminer reliability greater than 0.80 when the neurologists' examinations were 1 h apart; 2 of 7 achieved this level when the examinations were separated by 1 month. Interexaminer reliability between physical therapists was greater than 0.80 for 19 of 20 measures of strength and functional ability. Intraexaminer reliability coefficients greater than 0.80 were found for 13 of 24 sensory and reflex measures, 28 of 30 isometric strength measures, 24 of 30 timed tests and 5 of 6 coded ratings of functional ability. Electro-oculography, oral diadochokinetic syllable rates, hand and foot accelerometry, and tracings of sine and square waves were examined as quantitative indices of ataxia for patients with spinocerebellar degeneration. Of 11 measures of ataxia, only the oral diadochokinetic syllable rate test had acceptable reliability.
对30例夏科-马里-图思病（n = 30）、特发性多发性神经病（n = 16）和脊髓小脑变性（n = 30）患者的30项神经功能定量指标进行了检查者间和检查者内信度测定，这些指标包括感觉阈值、腱反射、最大等长肌力、定时测试以及功能能力的编码评分。当神经科医生的检查间隔为1小时时，6项感觉和反射指标中有5项的检查者间信度大于0.80；当检查间隔为1个月时，7项指标中有2项达到了这一水平。物理治疗师之间20项肌力和功能能力指标中有19项的检查者间信度大于0.80。在24项感觉和反射指标中有13项、30项等长肌力指标中有28项、30项定时测试中有24项以及6项功能能力编码评分中有5项的检查者内信度系数大于0.80。对脊髓小脑变性患者的眼电图、口腔快速重复音节率、手足加速度测量以及正弦波和方波描记进行了检查，作为共济失调的定量指标。在11项共济失调指标中，只有口腔快速重复音节率测试具有可接受的信度。
