Notermans N C, van Dijk G W, van der Graaf Y, van Gijn J, Wokke J H
University Hospital Utrecht, The Netherlands.
J Neurol Neurosurg Psychiatry. 1994 Jan;57(1):22-6. doi: 10.1136/jnnp.57.1.22.
To quantify ataxia in a simple way four tests were developed and analysed, based on the neurological examination: a tapping test for the arms (test 1), another one for the legs (test 2), a quantified finger-to-nose test (test 3), and a modified Romberg test (test 4). All tests were performed by 115 volunteers, 13 patients with cerebellar ataxia and 25 patients with sensory ataxia due to neuropathy. The test-retest repeatability was excellent. Tests 1, 2 and 4 were age-dependent, with lower scores above age 65. On test 1, 2 and 4 both groups of patients performed worse than controls; the correlation with the ataxia scale of Nobile-Orazio and the modified disability Rankin scale was good (P < 0.05). Although test 3 could differentiate between sensory and cerebellar ataxia, it was not useful for quantifying the degree of ataxia. To determine the practical value of the four tests, 11 patients performed the tests for a second time after a follow up period of 16 months. The results indicate that tests 1, 2 and 4 are sensitive for the detection of ataxia and of changes in its severity.
为了以一种简单的方式对共济失调进行量化，我们基于神经学检查开发并分析了四项测试：一项针对手臂的敲击测试（测试1）、另一项针对腿部的敲击测试（测试2）、一项量化的指鼻试验（测试3）以及一项改良的罗姆伯格试验（测试4）。所有测试均由115名志愿者、13名小脑性共济失调患者和25名因神经病变导致的感觉性共济失调患者完成。重测重复性极佳。测试1、2和4与年龄相关，65岁以上得分较低。在测试1、2和4中，两组患者的表现均比对照组差；与诺比利 - 奥拉齐奥共济失调量表和改良的残疾兰金量表的相关性良好（P < 0.05）。尽管测试3可以区分感觉性和小脑性共济失调，但它对量化共济失调程度并无帮助。为了确定这四项测试的实用价值，11名患者在16个月的随访期后再次进行了测试。结果表明，测试1、2和4对检测共济失调及其严重程度的变化很敏感。
