The complex relationship of Tribbles pseudokinase 1, PML/RARA and C/EBPα in leukemia: two possible couples but not a trio.
作者信息
Velasco Guillermo
机构信息
Department of Biochemistry and Molecular Biology I, School of Biology, Complutense University, Madrid, Spain Instituto de Investigaciones Sanitarias San Carlos (IdISSC), Madrid, Spain
出版信息
Haematologica. 2016 Oct;101(10):1129-1130. doi: 10.3324/haematol.2016.151654.
Abstract
摘要
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The complex relationship of Tribbles pseudokinase 1, PML/RARA and C/EBPα in leukemia: two possible couples but not a trio.白血病中Tribbles假激酶1、PML/RARA和C/EBPα之间的复杂关系：两对可能的组合，但并非三者协同关系。
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本文引用的文献
1
Co-operative leukemogenesis in acute myeloid leukemia and acute promyelocytic leukemia reveals C/EBPα as a common target of TRIB1 and PML/RARA.急性髓系白血病和急性早幼粒细胞白血病中的协同白血病发生揭示了C/EBPα是TRIB1和PML/RARA的共同靶点。
Haematologica. 2016 Oct;101(10):1228-1236. doi: 10.3324/haematol.2015.138503. Epub 2016 Jul 6.
2
Oncosuppressive functions of tribbles pseudokinase 3.TRIBBLE假激酶3的肿瘤抑制功能
Biochem Soc Trans. 2015 Oct;43(5):1122-6. doi: 10.1042/BST20150124.
3
Tribbles in normal and malignant haematopoiesis.正常及恶性造血过程中的Tribbles蛋白
Biochem Soc Trans. 2015 Oct;43(5):1112-5. doi: 10.1042/BST20150117.
4
Tribbles at the cross-roads….处于十字路口的Tribbles……
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New strategies in acute promyelocytic leukemia: moving to an entirely oral, chemotherapy-free upfront management approach.急性早幼粒细胞白血病的新策略：转向完全口服、无化疗的初始治疗方法。
Clin Cancer Res. 2014 Oct 1;20(19):4985-93. doi: 10.1158/1078-0432.CCR-13-2725.
6
Synergy against PML-RARa: targeting transcription, proteolysis, differentiation, and self-renewal in acute promyelocytic leukemia.协同作用对抗 PML-RARa：靶向转录、蛋白水解、分化和急性早幼粒细胞白血病的自我更新。
J Exp Med. 2013 Dec 16;210(13):2793-802. doi: 10.1084/jem.20131121.
7
Tribbles in acute leukemia.急性白血病中的类垂星体。
Blood. 2013 May 23;121(21):4265-70. doi: 10.1182/blood-2012-12-471300. Epub 2013 Apr 2.
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The Tribbles-1 protein in humans: roles and functions in health and disease.人类中的 Tribbles-1 蛋白：在健康和疾病中的作用和功能。
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Tribbles: 'puzzling' regulators of cell signalling.Tribbles：细胞信号转导的“令人费解”的调节剂。
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Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia.Tribbles 家族成员促进 C/EBPalpha 降解和诱导急性髓系白血病的差异能力。
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