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[头颈部癌症中免疫抑制因子(IAP-免疫抑制酸性蛋白,IS-免疫抑制物质)的临床评估]

[Clinical evaluation of immunosuppressive factors (IAP-immunosuppressive acidic protein, IS-immunosuppressive substance) in head and neck cancer].

作者信息

Saito T, Dake Y, Kakiuti H, Kato Y, Kuki K, Hayashi Y, Yokota M, Kinoshita K, Kuki S, Kimura T

出版信息

Nihon Jibiinkoka Gakkai Kaiho. 1989 Apr;92(4):588-96. doi: 10.3950/jibiinkoka.92.588.

DOI:10.3950/jibiinkoka.92.588
PMID:2769476
Abstract

It is reported that the levels of serum IAP and IS are useful parameters to evaluate the prognosis along with the clinical course of tumor bearing patients. Serum IAP and IS were examined in 149 patients with head and neck cancer. The level of serum IAP and IS increased in patients with not only advanced stages, but also poor prognosis. In general, the patients with death or recurrence had higher levels of serum IAP and IS than those with good prognosis. It is concluded that serum IAP and IS well reflect the immunological condition and clinical course of patients with cancer and may be one of the useful parameter for them.

摘要

据报道,血清IAP和IS水平是评估荷瘤患者预后及临床病程的有用参数。对149例头颈癌患者检测了血清IAP和IS。血清IAP和IS水平不仅在晚期患者中升高,而且在预后不良的患者中也升高。一般来说,死亡或复发患者的血清IAP和IS水平高于预后良好的患者。结论是血清IAP和IS能很好地反映癌症患者的免疫状况和临床病程,可能是评估这些患者的有用参数之一。

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