Buskila D, Gladman D D, Hannah W, Kahn H J
University of Toronto Rheumatic Disease Unit, Women's College, ON, Canada.
J Rheumatol. 1989 Jul;16(7):993-6.
Malignant lymphoma has been infrequently reported in the course of systemic lupus erythematosus (SLE). We report a case of primary malignant lymphoma of the spleen, an unusual site of primary lymphoma, complicating the course of systemic lupus erythematosus (SLE). Our patient had been treated with low dose prednisone and hydroxychloroquine only, and her lupus was quiescent at the time of presentation with the lymphoma. Thus primary malignant lymphoma should be considered in the differential diagnosis of splenomegaly in SLE.
恶性淋巴瘤在系统性红斑狼疮（SLE）病程中鲜有报道。我们报告一例脾脏原发性恶性淋巴瘤，这是原发性淋巴瘤的一个不常见部位，并发于系统性红斑狼疮（SLE）病程中。我们的患者仅接受了低剂量泼尼松和羟氯喹治疗，在出现淋巴瘤时其狼疮病情处于静止期。因此，在SLE脾肿大的鉴别诊断中应考虑原发性恶性淋巴瘤。
