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一项为期34年的全国性队列研究中腹股沟疝修补术的累积发病率及登记验证

Cumulative incidence and registry validation of groin hernia repair in a 34-year nationwide cohort.

作者信息

Burcharth Jakob, Liljekvist Mads Svane, Pommergaard Hans-Christian, Rosenberg Jacob

出版信息

Dan Med J. 2016 Oct;63(10).

PMID:27697133
Abstract

INTRODUCTION

The purpose of this study was to present a nationwide cumulative incidence and an age-specific incidence rate of groin hernia repair as well as to evaluate the validity of inguinal and femoral hernia operation codes in the Danish National Patient Registry (DNPR).

METHODS

All persons born in Denmark from 1977 to 2010 were investigated for groin hernia operations registered in the DNPR with respect to date of admission, operation, discharge and specific operation codes. To validate the predictive values of registrations, we randomly extracted data on elective and emergency groin hernia operations from the DNPR from 2005 to 2010 and examined the medical records.

RESULTS

The study population (n = 2,109,417) from 1977 to 2010 was followed from the primary groin hernia operation (n = 53,262) to 2010, yielding a total of 33.4 million person-years of follow-up. The probability of being operated for a groin hernia prior to the age of 34 years was 5.70% (95% confidence interval (CI): 5.62-5.78) for males and 1.26% (95% CI: 1.20-1.32) for females. The highest incidence rate was seen among males aged 0-1 years (10.19 (95% CI: 10.00-10.38)). The positive predictive value of patients registered with inguinal hernia operations in the DNPR who had been operated for an inguinal hernia was 100% (95% CI: 96-100%) and 91.3% (95% CI: 83-96%) for femoral hernia operations.

CONCLUSIONS

The incidence rate of groin hernia operations peaked at the 0-1 year age group in males and at the 3-4-year age group in females. Furthermore, the validation of the DNPR showed very high positive predictive values for both inguinal hernia operations and femoral hernia operations.

FUNDING

none.

TRIAL REGISTRATION

not relevant.

摘要

引言

本研究的目的是呈现全国范围内腹股沟疝修补术的累积发病率和特定年龄发病率,并评估丹麦国家患者登记处(DNPR)中腹股沟疝和股疝手术编码的有效性。

方法

对1977年至2010年在丹麦出生的所有人进行调查,以获取DNPR中登记的腹股沟疝手术的入院日期、手术日期、出院日期和特定手术编码。为验证登记的预测价值,我们从2005年至2010年的DNPR中随机提取择期和急诊腹股沟疝手术的数据,并检查病历。

结果

对1977年至2010年的研究人群(n = 2,109,417)进行随访,从首次腹股沟疝手术(n = 53,262)至2010年,共获得3340万人年的随访数据。34岁之前接受腹股沟疝手术的概率,男性为5.70%(95%置信区间(CI):5.62 - 5.78),女性为1.26%(95% CI:1.20 - 1.32)。0 - 1岁男性的发病率最高(10.19(95% CI:10.00 - 10.38))。在DNPR中登记为腹股沟疝手术且实际接受腹股沟疝手术的患者,其阳性预测值为100%(95% CI:96 - 100%),股疝手术的阳性预测值为91.3%(95% CI:83 - 96%)。

结论

腹股沟疝手术发病率在男性0 - 1岁年龄组和女性3 - 4岁年龄组达到峰值。此外,DNPR的验证显示腹股沟疝手术和股疝手术的阳性预测值都非常高。

资金来源

无。

试验注册

不相关。

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