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腹股沟疝亚型与双侧疝患者相关:一项为期14年的全国性流行病学研究。

Groin hernia subtypes are associated in patients with bilateral hernias: a 14-year nationwide epidemiologic study.

作者信息

Burcharth Jakob, Andresen Kristoffer, Pommergaard Hans-Christian, Rosenberg Jacob

机构信息

Centre for Perioperative Optimization, Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Copenhagen, Denmark,

出版信息

Surg Endosc. 2015 Jul;29(7):2019-26. doi: 10.1007/s00464-014-3905-z. Epub 2014 Oct 16.

Abstract

BACKGROUND

To investigate the relation between groin hernia subtypes in patients operated for bilateral hernias.

METHODS

With data from the Danish Hernia Database, we identified all patients operated for primary groin hernias from 1998 to 2012. Within this cohort all patients that were bilaterally operated were analyzed. Risk factors for bilateral groin hernia operation as well as the relationship between groin hernia subtypes bilaterally, were analyzed using multivariate Cox proportional hazards analysis and Kappa statistics.

RESULTS

A total of 108, 775 persons with primary groin hernia repair (89.9% males) were registered, and of those were 12,041 persons operated bilaterally (94.9% males). Females and males operated for a unilaterally direct inguinal hernia (DIH) had increased Hazard Ratios (HR) of 3.85 (CI 95% 2.14-6.19) and 4.46 (CI 95% 2.57-7.88) of being contralaterally operated for a DIH. Females and males operated for a unilaterally indirect inguinal hernia (IIH) had HRs of 6.93 (CI 95% 3.66-13.11) and 1.89 (CI95% 1.24-2.88) for being contralaterally operated for an IIH. The same tendency was seen for femoral hernias.

CONCLUSIONS

All hernia subtypes were bilaterally associated in both genders and the hernia subtypes could be localized manifestations of generalized conditions or inheritable traits instead of localized defects.

摘要

背景

研究双侧疝手术患者腹股沟疝亚型之间的关系。

方法

利用丹麦疝数据库的数据,我们确定了1998年至2012年期间所有接受原发性腹股沟疝手术的患者。在该队列中,对所有接受双侧手术的患者进行了分析。使用多变量Cox比例风险分析和Kappa统计分析双侧腹股沟疝手术的风险因素以及双侧腹股沟疝亚型之间的关系。

结果

共登记了108,775例接受原发性腹股沟疝修补术的患者(89.9%为男性),其中12,041例接受了双侧手术(94.9%为男性)。单侧直疝(DIH)手术的女性和男性对侧接受DIH手术的风险比(HR)分别增加3.85(95%CI 2.14 - 6.19)和4.46(95%CI 2.57 - 7.88)。单侧斜疝(IIH)手术的女性和男性对侧接受IIH手术的HR分别为6.93(95%CI 3.66 - 13.11)和1.89(95%CI 1.24 - 2.88)。股疝也呈现相同趋势。

结论

所有疝亚型在两性中均呈双侧关联,疝亚型可能是全身性疾病或遗传特征的局部表现,而非局部缺陷。

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