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A kinetic hairpin transfer model for parvoviral DNA replication.

作者信息

Chen K C, Tyson J J, Lederman M, Stout E R, Bates R C

机构信息

Department of Biology, Virginia Polytechnic Institute and State University, Blacksburg 24061.

出版信息

J Mol Biol. 1989 Jul 20;208(2):283-96. doi: 10.1016/0022-2836(89)90389-6.

DOI:10.1016/0022-2836(89)90389-6
PMID:2769758
Abstract

The DNAs encapsidated by parvoviruses show distinctly different patterns with respect to the ratio of plus-to-minus strands and sequence heterogeneity at the ends. A kinetic model, based on differential rates of hairpin transfer at 3' termini, is described and shown to account for all known parvoviral DNA distributions.

摘要

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