Ventura Tiago, Lopes Maria do Carmo, Ferreira Brigida Costa, Khouri Leila
Physics Department of University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal; Medical Physics Department, Instituto Português de Oncologia de Coimbra Francisco Gentil, EPE, Avenida Bissaya Barreto, n° 98, 3000-075 Coimbra, Portugal; Institute for Systems Engineering and Computers at Coimbra, Coimbra, Portugal.
School of Allied Health Technologies Polytechnic Institute of Porto, Rua Valente Perfeito, 322 4400-330 Vila Nova de Gaia, Portugal; Institute for Systems Engineering and Computers at Coimbra, Coimbra, Portugal.
Rep Pract Oncol Radiother. 2016 Nov-Dec;21(6):508-516. doi: 10.1016/j.rpor.2016.07.002. Epub 2016 Aug 24.
In this work, a graphical method for radiotherapy treatment plan assessment and comparison, named SPIDERplan, is proposed. It aims to support plan approval allowing independent and consistent comparisons of different treatment techniques, algorithms or treatment planning systems.
Optimized plans from modern radiotherapy are not easy to evaluate and compare because of their inherent multicriterial nature. The clinical decision on the best treatment plan is mostly based on subjective options.
SPIDERplan combines a graphical analysis with a scoring index. Customized radar plots based on the categorization of structures into groups and on the determination of individual structures scores are generated. To each group and structure, an angular amplitude is assigned expressing the clinical importance defined by the radiation oncologist. Completing the graphical evaluation, a global plan score, based on the structures score and their clinical weights, is determined. After a necessary clinical validation of the group weights, SPIDERplan efficacy, to compare and rank different plans, was tested through a planning exercise where plans had been generated for a nasal cavity case using different treatment planning systems.
SPIDERplan method was applied to the dose metrics achieved by the nasal cavity test plans. The generated diagrams and scores successfully ranked the plans according to the prescribed dose objectives and constraints and the radiation oncologist priorities, after a necessary clinical validation process.
SPIDERplan enables a fast and consistent evaluation of plan quality considering all targets and organs at risk.
在本研究中，提出了一种用于放射治疗计划评估和比较的图形方法，称为SPIDERplan。其目的是支持计划审批，允许对不同的治疗技术、算法或治疗计划系统进行独立且一致的比较。
现代放射治疗的优化计划由于其固有的多标准性质，不易评估和比较。关于最佳治疗计划的临床决策大多基于主观选择。
SPIDERplan将图形分析与评分指标相结合。基于将结构分类成组并确定各个结构得分，生成定制的雷达图。为每个组和结构分配一个角幅度，以表达放射肿瘤学家定义的临床重要性。在完成图形评估后，根据结构得分及其临床权重确定一个全局计划得分。在对组权重进行必要的临床验证后，通过一项计划演练测试了SPIDERplan在比较和排列不同计划方面的有效性，在该演练中，使用不同的治疗计划系统为一个鼻腔病例生成了计划。
将SPIDERplan方法应用于鼻腔测试计划所实现的剂量指标。在经过必要的临床验证过程后，生成的图表和得分根据规定的剂量目标、约束条件以及放射肿瘤学家的优先级成功地对计划进行了排序。
SPIDERplan能够在考虑所有靶区和危及器官的情况下，对计划质量进行快速且一致的评估。
