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统一剂量学指标(UDI):用于对治疗计划进行排序的一个品质因数。

Unified dosimetry index (UDI): a figure of merit for ranking treatment plans.

作者信息

Akpati Hilary, Kim ChangSeon, Kim Bong, Park Tae, Meek Allen

机构信息

Department of Radiation Oncology, Stony Brook University School of Medicine, Stony Brook, New York, U.S.A.

出版信息

J Appl Clin Med Phys. 2008 Jun 23;9(3):99-108. doi: 10.1120/jacmp.v9i3.2803.

Abstract

We have formulated a unified dosimetry index (UDI) that computes, for any given treatment plan, its deviations in terms of dose coverage, conformity, homogeneity, and dose gradient vis-à-vis an ideal plan (which we define as a dosimetry plan of perfect dose coverage, conformity, homogeneity, and step-wise fall-off to zero dose outside the planning target volume). In order to validate the UDI scoring system, 21 stereotactic cranial radiosurgery cases were evaluated retrospectively. The cases were planned on the BrainSCAN treatment planning system (BrainLAB, Feldkirchen, Germany) using 6 to 8 non-coplanar static beams collimated with the micro multi-leaf collimator (mMLC). We suggest a technique for creating a ranking system that can be utilized for plan evaluation and comparison between multiple plans. Under this system treatment plans are classified as "excellent", "good", "average", or "poor". The proposed ranking system can be utilized as a general guide for generating an optimal dosimetry plan for external beam radiation therapy.

摘要

我们制定了一个统一剂量学指数(UDI),对于任何给定的治疗计划,该指数能计算出其相对于理想计划(我们将其定义为具有完美剂量覆盖、适形性、均匀性且在计划靶体积之外剂量呈阶梯式下降至零的剂量学计划)在剂量覆盖、适形性、均匀性和剂量梯度方面的偏差。为了验证UDI评分系统,我们对21例立体定向颅部放射外科病例进行了回顾性评估。这些病例在BrainSCAN治疗计划系统(德国费尔德基兴的BrainLAB公司)上进行规划,使用6至8个非共面静态射束,并通过微型多叶准直器(mMLC)进行准直。我们提出了一种创建排名系统的技术,该系统可用于计划评估以及多个计划之间的比较。在这个系统下,治疗计划被分为“优秀”“良好”“中等”或“差”。所提出的排名系统可作为为外照射放射治疗生成最佳剂量学计划的一般指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c20f/5722298/bfdac6f94470/ACM2-9-099-g001.jpg

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