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焦虑症治疗中的综合疗法,特别强调肠道微生物群

Integrative Therapies in Anxiety Treatment with Special Emphasis on the Gut Microbiome.

作者信息

Schnorr Stephanie L, Bachner Harriet A

机构信息

Laboratories of Molecular Anthropology and Microbiome Research, Department of Anthropology, University of Oklahoma, Norman, OK, USA.

Department of Psychology and Counseling, Pittsburg State University, Pittsburg, KS, USA.

出版信息

Yale J Biol Med. 2016 Sep 30;89(3):397-422. eCollection 2016 Sep.

Abstract

Over the past decade, research has shown that diet and gut health affects symptoms expressed in stress related disorders, depression, and anxiety through changes in the gut microbiota. Psycho-behavioral function and somatic health interaction have often been ignored in health care with resulting deficits in treatment quality and outcomes. While mental health care requires the professional training in counseling, psychotherapy and psychiatry, complimentary therapeutic strategies, such as attention to a nutritional and diverse diet and supplementation of probiotic foods, may be integrated alongside psychotherapy treatment models. Development of these alternative strategies is predicated on experimental evidence and diligent research on the biology of stress, fear, anxiety-related behaviors, and the gut-brain connection. This article provides a brief overview on biological markers of anxiety and the expanding nutritional literature relating to brain health and mental disorders. A case study demonstrates an example of a biopsychosocial approach integrating cognitive psychotherapy, dietary changes, and mindfulness activities, in treating symptoms of anxiety. This case study shows a possible treatment protocol to explore the efficacy of targeting the gut-brain-axis that may be used as an impetus for future controlled studies.

摘要

在过去十年中,研究表明饮食和肠道健康通过肠道微生物群的变化影响与压力相关的疾病、抑郁症和焦虑症中表现出的症状。心理行为功能和躯体健康的相互作用在医疗保健中常常被忽视,导致治疗质量和效果存在缺陷。虽然心理健康护理需要在咨询、心理治疗和精神病学方面接受专业培训,但补充性治疗策略,如关注营养丰富且多样的饮食以及补充益生菌食品,可以与心理治疗模式相结合。这些替代策略的发展基于实验证据以及对压力、恐惧、焦虑相关行为和肠脑连接生物学的深入研究。本文简要概述了焦虑的生物学标志物以及与大脑健康和精神障碍相关的不断扩展的营养文献。一个案例研究展示了一种生物心理社会方法的示例,该方法整合了认知心理治疗、饮食改变和正念活动来治疗焦虑症状。这个案例研究展示了一种可能的治疗方案,以探索针对肠脑轴的疗效,这可能会推动未来的对照研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cf3/5045149/4d5e24a57511/yjbm_89_3_397_g01.jpg

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