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韦伦多夫菌株的基因组序列草图表明其具有异养多功能性和生物修复潜力。

Draft genome sequence of strain Wellendorf implicates heterotrophic versatility and bioremediation potential.

作者信息

Avramov Anton P, Couger M B, Hartley Emily L, Land Craig, Wellendorf Rachel, Hanafy Radwa A, Budd Connie, French Donald P, Hoff Wouter D, Youssef Noha

机构信息

Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, United States.

Department of Integrative Biology, Oklahoma State University, Stillwater, OK, United States.

出版信息

Genom Data. 2016 Sep 17;10:54-60. doi: 10.1016/j.gdata.2016.09.005. eCollection 2016 Dec.

Abstract

is a predominant member of hydrocarbon-contaminated environments. We here report on the genomic analysis of strain Wellendorf that was isolated from an indoor door handle. The partial genome of strain Wellendorf consists of 2,916,870 bp of DNA with 2831 protein-coding genes and 49 RNA genes. The organism appears to be a versatile mesophilic heterotroph potentially capable of hydrolysis a suite of carbohydrates and amino acids. Genomic analysis revealed metabolic versatility with genes involved in the metabolism and transport of glucose, fructose, rhamnose, galactose, xylose, arabinose, alanine, aspartate, asparagine, glutamate, serine, glycine, threonine and cysteine. This is the first detailed analysis of a genome.

摘要

是碳氢化合物污染环境中的主要成员。我们在此报告从室内门把手分离出的韦伦多夫菌株的基因组分析。韦伦多夫菌株的部分基因组由2916870个碱基对的DNA组成,有2831个蛋白质编码基因和49个RNA基因。该生物体似乎是一种多功能嗜温异养生物,可能能够水解一系列碳水化合物和氨基酸。基因组分析揭示了其代谢多功能性,涉及葡萄糖、果糖、鼠李糖、半乳糖、木糖、阿拉伯糖、丙氨酸、天冬氨酸、天冬酰胺、谷氨酸、丝氨酸、甘氨酸、苏氨酸和半胱氨酸代谢及转运的基因。这是对该基因组的首次详细分析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70eb/5035333/e8377a8bb674/gr1.jpg

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