Gong Jia Qing, Cao Yong Kuan, Zhang Guo Hu, Wang Pei Hong, Luo Guo De
a Center of General Surgery , The People's Liberation Army General Hospital of Chengdu Command , Chengdu, Sichuan Province , China.
J Invest Surg. 2017 Apr;30(2):125-132. doi: 10.1080/08941939.2016.1230249. Epub 2016 Oct 4.
Currently, there is no optimal digestive tract reconstruction technique well recognized by scholars after total gastrectomy. In this study, a new reconstruction method, which is modified from the classic Roux-en-Y procedure, an uncut jejunal esophageal anastomosis with double jejunal pouch (UJEA-DJP) was established, and its advantages for improving the quality of life of patients who undergo total gastrectomy were analyzed.
Altogether 160 patients with gastric cancer enrolled in our center from September 2009 to March 2012 received radical D2 total gastrectomy. According to the reconstruction methods used, these patients were divided into three groups: UJEA-DJP (n = 63), Roux-en-Y (n = 45), and P-loop with Roux-en-Y esophagojejunostomy (P-RY; n = 52). The operation time for reconstruction, complications, prognostic nutritional index (PNI), and the Visick classification among the three groups were analyzed.
We found that UJEA-DJP has advantages over Roux-en-Y and P-RY regarding the time of digestive tract reconstruction, incidence rates for long-term complications, postoperative nutritional index, body weight recovery, and the Visick classification for subjective feelings (p < .05).
The UJEA-DJP surgical procedure has the advantages of intestinal continuity and double-pouch construction, which can significantly reduce long-term complications and improve the long-term quality of life of patients after surgical procedure.
目前,全胃切除术后尚无一种得到学者广泛认可的最佳消化道重建技术。本研究建立了一种新的重建方法,即改良经典的Roux-en-Y术式,采用未离断空肠食管吻合加双空肠袋(UJEA-DJP),并分析其在改善全胃切除患者生活质量方面的优势。
2009年9月至2012年3月在本中心登记的160例胃癌患者接受了D2根治性全胃切除术。根据所采用的重建方法,将这些患者分为三组:UJEA-DJP组(n = 63)、Roux-en-Y组(n = 45)和P袢Roux-en-Y食管空肠吻合术组(P-RY组;n = 52)。分析了三组之间的重建手术时间、并发症、预后营养指数(PNI)和Visick分级。
我们发现,在消化道重建时间、远期并发症发生率、术后营养指数、体重恢复以及主观感受的Visick分级方面,UJEA-DJP组优于Roux-en-Y组和P-RY组(p <.05)。
UJEA-DJP手术具有肠道连续性和双袋构建的优点,可显著减少远期并发症,提高患者术后的远期生活质量。