Chen Wei, Jiang Xumian, Huang Hui, Ding Zao, Li Chihua
Department of Gastrointestinal Surgery, The Central Hospital of the Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, People's Republic of China.
Department of General Surgery, Zhongnan Hospital of Wuhan University, Wuhan, 430014, People's Republic of China.
BMC Surg. 2018 Aug 20;18(1):63. doi: 10.1186/s12893-018-0397-0.
No consensus exists regarding the best reconstruction style after total gastrectomy (TG). Roux-en-Y oesophagojejunostomy is a simple option for gastrointestinal tract reconstruction. Recently, jejunal pouch reconstruction has been suggested as an appropriate approach. We compared the postoperative outcomes of the two surgical approaches using a well-characterized cohort of gastric carcinoma patients.
A total of 60 patients who underwent TG were divided into two groups according to the reconstruction style. Both groups were compared regarding patient characteristics, perioperative data and quality of life (QoL), which was assessed using the Spitzer QoL index (QLI) and Visick grade. The incidence of long-term surgery-related complications, including reflux oesophagitis, dumping syndrome, and retention syndrome, was also compared to evaluate postoperative restoration.
Both study groups were comparable with respect to general patient characteristics. No mortality or no significant differences in surgery-related data were found except in the operation time. Compared to Orr Roux-en-Y reconstruction, pouch reconstruction was associated with a longer procedure time, a lower incidence of dumping/retention syndrome and better QoL parameters (p < 0.05).
In this study, jejunal pouch reconstruction after TG was superior to the traditional Roux-n-Y oesophagojejunostomy with respect to improved dietary intake and QoL.
关于全胃切除术后(TG)最佳重建方式尚无共识。Roux-en-Y食管空肠吻合术是胃肠道重建的一种简单选择。最近,空肠袋重建被认为是一种合适的方法。我们使用一组特征明确的胃癌患者比较了两种手术方式的术后结果。
根据重建方式将60例行全胃切除术的患者分为两组。比较两组患者的特征、围手术期数据和生活质量(QoL),生活质量采用Spitzer生活质量指数(QLI)和Visick分级进行评估。还比较了包括反流性食管炎、倾倒综合征和潴留综合征在内的长期手术相关并发症的发生率,以评估术后恢复情况。
两个研究组在一般患者特征方面具有可比性。除手术时间外,未发现死亡率或手术相关数据有显著差异。与Orr Roux-en-Y重建相比,袋状重建手术时间更长,倾倒/潴留综合征发生率更低,生活质量参数更好(p<0.05)。
在本研究中,全胃切除术后空肠袋重建在改善饮食摄入和生活质量方面优于传统的Roux-n-Y食管空肠吻合术。