Gong JiaQing, Wang Bin, Wang JunQing, Li YunMing, Cao YongKuan, Li Wei, Shang Min, Huang Ling
Department of General Surgery, ChengDu XinHua Hospital, ChengDu, Sichuan Province, China.
Department of Radiology, The General Hospital of Western Theater Command, ChengDu, Sichuan Province, China.
J Invest Surg. 2022 Feb;35(2):293-300. doi: 10.1080/08941939.2020.1854397. Epub 2020 Dec 20.
Currently, there is no optimal digestive tract reconstruction technique well recognized by scholars after distal gastrectomy. A new reconstruction method, which was modified from the classic Roux-en-Y procedure, the continuous jejunal pouch and residual stomach anastomosis combined with jejunal lateral anastomosis (Contin-L), was established. In order to fully clarify the superiority of this procedure, this study has conducted a systematic analysis and prepared a summary of the clinical data of patients who underwent distal gastrectomy for gastric cancer.
From June 2013 to March 2016, we enrolled 198 patients with gastric cancer who underwent radical D2 distal gastrectomy. According to the reconstruction methods, these patients were divided into three groups: Contin-L (n = 74), Billroth II (n = 59), and Roux-en-Y (n = 65) groups. The operation time for reconstruction, complications, prognostic nutritional index (PNI), and the Visick grading were analyzed.
Regarding long-term complications, such as reflux gastritis, the Contin-L procedure showed significantly better results than Billroth II (p < 0.0001). Regarding the long-term postoperative nutritional status, such as the PNI and body weight recovery, the Contin-L procedure displayed significantly better results than Billroth II and Roux-en-Y (p < 0.05). Postoperative subjective feelings evaluated by Visick grading were significantly more improved in the Contin-L than in the Billroth II and Roux-en-Y groups (p ≤ 0.01).
The Contin-L procedure gave full play to the advantages of jejunal continuity, and pouch and lateral anastomoses, which significantly reduced short- and long-term complications, and improved the long-term patient quality of life following the surgical procedure.
目前,远端胃切除术后尚无一种被学者广泛认可的最佳消化道重建技术。我们建立了一种新的重建方法,它是在经典的Roux-en-Y手术基础上改良而来,即连续空肠袋与残胃吻合联合空肠侧侧吻合术(Contin-L)。为充分阐明该手术的优势,本研究对接受远端胃癌切除术患者的临床资料进行了系统分析并做了总结。
2013年6月至2016年3月,我们纳入了198例行根治性D2远端胃癌切除术的患者。根据重建方法,将这些患者分为三组:Contin-L组(n = 74)、毕罗Ⅱ式组(n = 59)和Roux-en-Y组(n = 65)。分析重建手术时间、并发症、预后营养指数(PNI)及Visick分级。
在反流性胃炎等远期并发症方面,Contin-L手术的效果明显优于毕罗Ⅱ式手术(p < 0.0001)。在术后远期营养状况,如PNI和体重恢复方面,Contin-L手术的效果明显优于毕罗Ⅱ式手术和Roux-en-Y手术(p < 0.05)。通过Visick分级评估的术后主观感受,Contin-L组比毕罗Ⅱ式组和Roux-en-Y组有更显著的改善(p≤0.01)。
Contin-L手术充分发挥了空肠连续性、袋状吻合和侧侧吻合的优势,显著减少了近期和远期并发症,提高了患者术后的长期生活质量。