Msellati P, Touré A, Sow M S, Cécé K, Taverne B, Desclaux A, Barry M, Etard J-F, Delaporte E
TransVIHMI (UMI 233 IRD, U 1175 Inserm), université de Montpellier, 34090, Montpellier, France.
PACCI, CHU de Treichville, 18 BP 1954, Abidjan, Côte d'Ivoire.
Bull Soc Pathol Exot. 2016 Oct;109(4):236-243. doi: 10.1007/s13149-016-0526-x. Epub 2016 Oct 3.
Ebola virus disease (EVD) epidemic that spread in West Africa from the end of 2013 to early 2016 has reached more people than all past epidemics. Beyond care management of acute phase ill patients and measures for the control of the epidemic, the outcome of Ebola survivors became an important question as their number increased and raised new issues. A multidisciplinary prospective cohort of survivors in Guinea has been launched by IRD UMI 233 and Donka National Hospital, Conakry, Guinea, to assess the long-term clinical, psychological, sociological, immunological, and viral outcomes potentially related to EVD. This paper describes PostEboGui Programme, constraints and changes to the initial proposal, participants, first results, and new issues, 1 year after its start, in a descriptive and critical view. We started also to work on ethical aspects in the context of epidemics and of mass interventions with a risk of overinvestigation of patients.
2013年底至2016年初在西非蔓延的埃博拉病毒病（EVD）疫情波及的人数超过了以往所有疫情。除了急性期患病患者的护理管理和疫情控制措施外，随着埃博拉幸存者人数的增加及其引发的新问题，幸存者的预后成为一个重要问题。法国国家科研中心（IRD）的UMI 233以及几内亚科纳克里的东卡国立医院发起了一项针对几内亚幸存者的多学科前瞻性队列研究，以评估可能与埃博拉病毒病相关的长期临床、心理、社会学、免疫学和病毒学预后。本文以描述性和批判性视角，介绍了PostEboGui项目、初始方案的限制因素和变化、参与者、初步结果以及项目启动1年后出现的新问题。我们还开始研究疫情背景下以及存在对患者过度检查风险的大规模干预措施中的伦理问题。
