Buchacz Kate, Farrior Jennifer, Beauchamp Geetha, McKinstry Laura, Kurth Ann E, Zingman Barry S, Gordin Fred M, Donnell Deborah, Mayer Kenneth H, El-Sadr Wafaa M, Branson Bernard
1 Division of HIV/AIDS Prevention, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
2 FHI360, Durham, NC, USA.
J Int Assoc Provid AIDS Care. 2017 Jan/Feb;16(1):81-90. doi: 10.1177/2325957416671410. Epub 2016 Oct 5.
As part of the HPTN 065 study in the Bronx, New York and Washington, the authors, we surveyed clinicians to assess for shifts in their practices and attitudes around HIV treatment and prevention. Antiretroviral therapy (ART)-prescribing clinicians at 39 HIV care sites were offered an anonymous Web-based survey at baseline (2010-2011) and at follow-up (2013). The 165 respondents at baseline and 141 respondents at follow-up had similar characteristics-almost 60% were female, median age was 47 years, two-thirds were physicians, and nearly 80% were HIV specialists. The percentage who reported recommending ART irrespective of CD4 count was higher at follow-up (15% versus 68%), as was the percentage who would initiate ART earlier for patients having unprotected sex with partners of unknown HIV status (64% versus 82%), and for those in HIV-discordant partnerships (75% versus 87%). In line with changing HIV treatment guidelines during 2010 to 2013, clinicians increasingly supported early ART for treatment and prevention.
作为在纽约布朗克斯区和华盛顿开展的HPTN 065研究的一部分，我们（作者）对临床医生进行了调查，以评估他们在艾滋病治疗和预防方面的实践和态度变化。在39个艾滋病护理点，为开具抗逆转录病毒疗法（ART）的临床医生在基线期（2010 - 2011年）和随访期（2013年）提供了一项匿名的网络调查。基线期的165名受访者和随访期的141名受访者具有相似特征——近60%为女性，年龄中位数为47岁，三分之二是医生，近80%是艾滋病专家。报告称无论CD4细胞计数如何都会推荐ART的比例在随访期更高（15%对68%），对于与艾滋病毒状况不明的伴侣发生无保护性行为的患者（64%对82%）以及处于艾滋病毒不一致伴侣关系中的患者（75%对87%），会更早开始ART的比例也是如此。与2010年至2013年期间不断变化的艾滋病治疗指南一致，临床医生越来越支持早期ART用于治疗和预防。
