老年人衰弱表型各组成部分发生率及决定因素的性别差异：西班牙裔老年人健康与老龄化趋势研究（SABE研究）的结果
Gender Differences in the Incidence and Determinants of Components of the Frailty Phenotype Among Older Adults: Findings From the SABE Study.
作者信息
Alexandre Tiago da S, Corona Ligiana P, Brito Tábatta R P, Santos Jair L F, Duarte Yeda A O, Lebrão Maria L
机构信息
1 Federal University of Sao Carlos, Sao Carlos, Brazil.
2 University of Campinas, Limeira, Brazil.
出版信息
J Aging Health. 2018 Feb;30(2):190-212. doi: 10.1177/0898264316671228. Epub 2016 Oct 4.
OBJECTIVE
To analyze gender differences in incidence and determinants of the components of the frailty phenotype.
METHOD
A total of 1,413 older adults were selected in 2006. To estimate the incidence of each frailty component, only individuals who did not exhibit a given component at baseline (independently of the presence of other components) were included in the study. The variables of interest were socioeconomic, behavioral, clinical, anthropometric factors and physical performance. The incidence of each component in 2010 was the outcome.
RESULTS
Unintentional weight loss and slowness were more incident in men up to 74 years of age. The other frailty components were more incident in women at all age groups, except weakness. Besides age, the determinants of incidence of the components of frailty were different between genders.
DISCUSSION
Strategies for preventing or delaying the installation of frailty need to address gender differences, considering the greater complexity in the network determinants among women.
目的
分析衰弱表型各组成部分在发病率及决定因素方面的性别差异。
方法
2006年共选取了1413名老年人。为估算各衰弱组成部分的发病率，研究仅纳入了在基线时未表现出特定组成部分（无论其他组成部分是否存在）的个体。感兴趣的变量包括社会经济、行为、临床、人体测量因素及身体机能。2010年各组成部分的发病率为研究结果。
结果
74岁及以下男性中，非故意体重减轻和行动迟缓更为常见。除虚弱外，其他衰弱组成部分在各年龄组女性中更为常见。除年龄外，衰弱各组成部分发病率的决定因素在性别间存在差异。
讨论
考虑到女性网络决定因素更为复杂，预防或延缓衰弱发生的策略需要考虑性别差异。
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