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谨防HELLP综合征颅内血肿后出现延迟性严重脑肿胀。

Beware of delayed severe brain swelling after intracerebral haematoma in HELLP syndrome.

作者信息

Gioffrè G, Bodkin P A, Labram E K, Shetty A

机构信息

Department of Neurosurgery, Aberdeen Royal Infirmary.

Department of Obstetrics and Gynaecology, Aberdeen Maternity Hospital , Aberdeen , UK.

出版信息

Obstet Med. 2013 Sep;6(3):129-131. doi: 10.1258/om.2012.110030. Epub 2013 May 3.

Abstract

Haemolysis, elevated liver enzymes and low platelets (HELLP) syndrome is a condition associated with increased risk of adverse outcomes during pregnancy and peripartum, including neurological complications. We report the third case in the world literature of delayed brain swelling following cerebral haemorrhage as a complication of HELLP syndrome. A 36-year-old woman in labour developed HELLP, which was complicated with intracerebral haematoma. This was evacuated, but motor impairment persisted after surgery and unfortunately the patient died unexpectedly during the 11th postoperative day. Computer tomographic brain scans documented diffuse cerebral swelling, which we think may have been caused by cerebral vasospasm. Cerebral vasospasm should always be considered when managing patients who suffered from stroke complicating HELLP syndrome. Close monitoring is advised even in later stages of recovery.

摘要

溶血、肝酶升高和血小板减少(HELLP)综合征是一种与妊娠和围产期不良结局风险增加相关的病症,包括神经并发症。我们报告了世界文献中第三例因HELLP综合征并发症脑出血后出现延迟性脑肿胀的病例。一名36岁的产妇发生了HELLP,并并发脑内血肿。血肿被清除,但术后运动功能障碍持续存在,不幸的是患者在术后第11天意外死亡。脑部计算机断层扫描记录了弥漫性脑肿胀,我们认为这可能是由脑血管痉挛引起的。在处理患有HELLP综合征并发中风的患者时,应始终考虑脑血管痉挛。即使在恢复后期也建议密切监测。

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本文引用的文献

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HELLP syndrome: the state of the art.
Obstet Gynecol Surv. 2004 Dec;59(12):838-45. doi: 10.1097/01.ogx.0000146948.19308.c5.
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Cerebral haemodynamic pathologies in HELLP syndrome.HELLP综合征中的脑血流动力学病变
Clin Neurol Neurosurg. 2003 Sep;105(4):256-61. doi: 10.1016/s0303-8467(03)00043-x.
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HELLP syndrome with haemaglobin vasospasm.伴有血红蛋白血管痉挛的HELLP综合征
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