Walters Kristen M, Woessner Katharine M
Department of Allergy, Asthma & Immunology, Scripps Clinic, 3811 Valley Centre Drive, San Diego, CA 92130, USA.
Department of Allergy, Asthma & Immunology, Scripps Clinic, 3811 Valley Centre Drive, San Diego, CA 92130, USA.
Immunol Allergy Clin North Am. 2016 Nov;36(4):625-641. doi: 10.1016/j.iac.2016.06.001.
Nonsteroidal antiinflammatory drugs (NSAIDs), including aspirin, are among the most commonly used drugs worldwide. They account for a large number of adverse drug reactions (ADRs). The prevalence of NSAID-induced reactions is increasing. Distinguishing between a predicted side effect of a drug and a potentially life-threatening hypersensitivity reaction is essential to manage the affected patient. However, most clinicians find it difficult to diagnose these types of reactions despite published classification schemes. In this overview, we provide an in-depth review of NSAID classification, types of NSAID reactions, diagnostic tactics, and management strategies to provide the reader with a greater understanding of NSAID-induced reactions.
包括阿司匹林在内的非甾体抗炎药（NSAIDs）是全球使用最广泛的药物之一。它们导致了大量的药物不良反应（ADR）。NSAID引起的反应发生率正在上升。区分药物的预期副作用和潜在的危及生命的过敏反应对于治疗受影响的患者至关重要。然而，尽管有已发表的分类方案，大多数临床医生仍发现难以诊断这些类型的反应。在本综述中，我们对NSAID的分类、NSAID反应的类型、诊断策略和管理策略进行了深入回顾，以便让读者更好地了解NSAID引起的反应。
