Brandão Lara A, Castillo Mauricio
Radiologic Department, Clínica Felippe Mattoso, Fleury Medicina Diagnóstica, Avenida das Américas 700, sala 320, Barra Da Tijuca, Rio De Janeiro, Rio De Janeiro CEP 22640-100, Brazil; Radiologic Department, Clínica IRM-Ressonância Magnética, Rua Capitão Salomão, Humaitá, Rio De Janeiro, Rio De Janeiro CEP 22271-040, Brazil.
Division of Neuroradiology, Department of Radiology, University of North Carolina School of Medicine, Room 3326, Old Infirmary Building, Manning Drive, Chapel Hill, NC 27599-7510, USA.
Neuroimaging Clin N Am. 2016 Nov;26(4):511-536. doi: 10.1016/j.nic.2016.06.004. Epub 2016 Sep 6.
Primary central nervous system lymphomas are aggressive, high-cell-density tumors. There is recent increase in their incidence in immunocompetent patients. Knowledge of imaging findings on computed tomography and conventional MR imaging is important to suggest the diagnosis. Moreover, information obtained from advanced MR imaging techniques, such as diffusion-weighted imaging, diffusion tensor imaging, MR spectroscopy, perfusion-weighted imaging, and dynamic contrast-enhanced studies, increases diagnostic confidence and helps distinguish them from other aggressive intracranial tumors. This article discusses typical imaging findings of primary and secondary central nervous system lymphomas on computed tomography and conventional MR imaging, advanced MR imaging techniques, and changes related to steroid therapy.
原发性中枢神经系统淋巴瘤是侵袭性、高细胞密度肿瘤。免疫功能正常患者中其发病率近期有所上升。了解计算机断层扫描和传统磁共振成像的影像学表现对于提示诊断很重要。此外，从先进的磁共振成像技术，如扩散加权成像、扩散张量成像、磁共振波谱、灌注加权成像和动态对比增强研究中获得的信息，可提高诊断信心，并有助于将它们与其他侵袭性颅内肿瘤区分开来。本文讨论原发性和继发性中枢神经系统淋巴瘤在计算机断层扫描、传统磁共振成像、先进磁共振成像技术以及与类固醇治疗相关变化方面的典型影像学表现。
