Department of radiodiagnosis, Lokmanya Tilak Municipal Medical College and General hospital, Sion, Mumbai, India.
J Radiol Case Rep. 2022 Jul 31;16(7):1-17. doi: 10.3941/jrcr.v16i7.4562. eCollection 2022 Jul.
Primary central nervous system lymphoma (PCNSL) constitutes about 3% of all primary brain tumors and nearly 1 to 3% of all Non Hodgkin Lymphomas. In the recent years the incidence of primary CNS lymphoma is increasing in immunocompetent patients. As PCNSL are chemosensitive as well as radiosensitive, its early and accurate diagnosis is imperative for optimal management. Contrast enhanced Magnetic Resonance Imaging (MRI) is the recommended imaging modality for PCNSL; however, contrast enhanced Computed Tomography (CE-CT) is done in cases where MRI is contraindicated. Advanced imaging techniques like DWI (diffusion weighted imaging), MRS (MR Spectroscopy), MR perfusion, DTI (Diffusion tensor imaging) are important in diagnosis and help in its differentiation from other tumors.
原发性中枢神经系统淋巴瘤（PCNSL）约占所有原发性脑肿瘤的 3%，几乎占所有非霍奇金淋巴瘤的 1%至 3%。近年来，免疫功能正常患者中原发性中枢神经系统淋巴瘤的发病率正在增加。由于 PCNSL 对化疗和放疗敏感，因此早期、准确的诊断对于最佳治疗至关重要。增强磁共振成像（MRI）是 PCNSL 的推荐成像方式；但是，在 MRI 禁忌的情况下，会进行增强计算机断层扫描（CE-CT）。扩散加权成像（DWI）、磁共振波谱（MRS）、磁共振灌注、弥散张量成像（DTI）等高级成像技术在诊断中很重要，有助于与其他肿瘤区分开来。
