Neri Mauro, Villa Gianluca, Garzotto Francesco, Bagshaw Sean, Bellomo Rinaldo, Cerda Jorge, Ferrari Fiorenza, Guggia Silvia, Joannidis Michael, Kellum John, Kim Jeong Chul, Mehta Ravindra L, Ricci Zaccaria, Trevisani Alberto, Marafon Silvio, Clark William R, Vincent Jean-Louis, Ronco Claudio
Department of Nephrology, Dialysis and Transplantation, International Renal Research Institute of Vicenza, San Bortolo Hospital, Viale Rodolfi 37, Vicenza, 36100, Italy.
Department of Management and Engineering, University of Padova, Vicenza, Italy.
Crit Care. 2016 Oct 10;20(1):318. doi: 10.1186/s13054-016-1489-9.
This article reports the conclusions of a consensus expert conference on the basic principles and nomenclature of renal replacement therapy (RRT) currently utilized to manage acute kidney injury (AKI). This multidisciplinary consensus conference discusses common definitions, components, techniques, and operations of the machines and platforms used to deliver extracorporeal therapies, utilizing a "machine-centric" rather than a "patient-centric" approach. We provide a detailed description of the performance characteristics of membranes, filters, transmembrane transport of solutes and fluid, flows, and methods of measurement of delivered treatment, focusing on continuous renal replacement therapies (CRRT) which are utilized in the management of critically ill patients with AKI. This is a consensus report on nomenclature harmonization for principles of extracorporeal renal replacement therapies. Devices and operations are classified and defined in detail to serve as guidelines for future use of terminology in papers and research.
本文报告了一次关于目前用于治疗急性肾损伤（AKI）的肾脏替代治疗（RRT）基本原则和术语的共识专家会议的结论。本次多学科共识会议采用“以机器为中心”而非“以患者为中心”的方法，讨论了用于提供体外治疗的机器和平台的通用定义、组件、技术及操作。我们详细描述了膜、滤器的性能特征，溶质和液体的跨膜转运、流量以及所提供治疗的测量方法，重点关注用于治疗重症AKI患者的连续性肾脏替代治疗（CRRT）。这是一份关于体外肾脏替代治疗原则术语协调的共识报告。对设备和操作进行了详细分类和定义，作为未来论文和研究中术语使用的指南。
