Wang Zhun, Cai Qiliang, Li Gang, Jiang Ning, Niu Yuanjie
Department of Urology, The Second Hospital of Tianjin Medical University, Tianjin Institute of Urology, Tianjin, China.
Department of Urology, The Second Hospital of Tianjin Medical University, Tianjin Institute of Urology, Tianjin, China.
Urology. 2017 Jan;99:e17-e19. doi: 10.1016/j.urology.2016.08.021. Epub 2016 Oct 5.
We present a rare case of silent giant pheochromocytoma with leukemoid reaction that has not been reported before. The patient was a 61-year-old woman who complained of progressive weight loss for 3 months. Preoperatively the urine vanillylmandelic acid was 105.54 mg/24 hours. White blood cell count was 56.9 × 10/L. Abdominal ultrasound and computed tomography revealed a mass measuring 18 × 11 cm in the left adrenal area. The patient underwent adrenal gland neoplasm resection. Postoperative histopathologic evaluation confirmed the diagnosis of pheochromocytoma. The leukocyte dropped to normal gradually in 10 days after the operation. Giant pheochromocytoma with leukemoid reaction was very rare. Resection is the only curative treatment.
我们报告一例罕见的无症状巨大嗜铬细胞瘤伴类白血病反应，此前未见报道。患者为一名61岁女性，主诉3个月来体重逐渐减轻。术前尿香草扁桃酸为105.54mg/24小时。白细胞计数为56.9×10⁹/L。腹部超声和计算机断层扫描显示左肾上腺区有一个18×11cm的肿块。患者接受了肾上腺肿瘤切除术。术后组织病理学评估证实为嗜铬细胞瘤。术后10天白细胞逐渐降至正常。巨大嗜铬细胞瘤伴类白血病反应非常罕见。手术切除是唯一的治愈性治疗方法。
