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嗜铬细胞瘤伪装成急性冠状动脉综合征:一例报告

Pheochromocytoma Mimicking Acute Coronary Syndrome: A Case Report.

作者信息

Cheng Yanwei, Qin Lijie, Chen Long

机构信息

Department of Emergency, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, China.

出版信息

Front Oncol. 2022 Apr 13;12:879714. doi: 10.3389/fonc.2022.879714. eCollection 2022.

DOI:10.3389/fonc.2022.879714
PMID:35494087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9043547/
Abstract

Pheochromocytoma is a rare catecholamine-secreting tumor with highly variable clinical presentations. We herein report a patient who presented to the emergency department with precordia pain, elevated myocardial enzymes, T-wave inversions on electrocardiogram and segmental ventricular wall motion abnormalities on echocardiography, which is normally managed as suspected acute coronary syndrome (ACS). However, the urgent coronary angiography showed normal coronary arteries. During his hospital stay, a sudden increase in blood pressure allowed us to suspect a pheochromocytoma, which was confirmed by elevated levels of catecholamines and by the finding of a right adrenal mass on magnetic resonance imaging. The tumor was successfully excised and the patient is now asymptomatic. This case illustrates that pheochromocytoma can present as a mimic of ACS but this is often difficult to diagnose at first glance and often misleads clinicians into making an incorrect diagnosis. In addition, clinicians should be familiar with clinical manifestations of pheochromocytoma, which can help raise clinical suspicion and facilitate the early diagnosis and treatment of pheochromocytoma.

摘要

嗜铬细胞瘤是一种罕见的分泌儿茶酚胺的肿瘤,临床表现高度多变。我们在此报告一名患者,该患者因心前区疼痛、心肌酶升高、心电图T波倒置以及超声心动图显示节段性室壁运动异常而就诊于急诊科,通常这些表现被当作疑似急性冠状动脉综合征(ACS)来处理。然而,紧急冠状动脉造影显示冠状动脉正常。在其住院期间,血压突然升高使我们怀疑患有嗜铬细胞瘤,这一怀疑通过儿茶酚胺水平升高以及磁共振成像发现右侧肾上腺肿块得以证实。肿瘤被成功切除,患者现在无症状。该病例表明,嗜铬细胞瘤可表现为类似ACS,但乍一看往往难以诊断,且常常误导临床医生做出错误诊断。此外,临床医生应熟悉嗜铬细胞瘤的临床表现,这有助于提高临床怀疑并促进嗜铬细胞瘤的早期诊断和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2438/9043547/a3b6168294e4/fonc-12-879714-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2438/9043547/73fd8e5b735e/fonc-12-879714-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2438/9043547/89c4768c8ded/fonc-12-879714-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2438/9043547/a3b6168294e4/fonc-12-879714-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2438/9043547/73fd8e5b735e/fonc-12-879714-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2438/9043547/89c4768c8ded/fonc-12-879714-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2438/9043547/a3b6168294e4/fonc-12-879714-g003.jpg

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本文引用的文献

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Rev Cardiovasc Med. 2021 Dec 22;22(4):1215-1228. doi: 10.31083/j.rcm2204130.
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J Clin Med. 2020 Jul 30;9(8):2435. doi: 10.3390/jcm9082435.
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Adrenal incidentaloma or epinephroma and review of the literature. Differential diagnosis of adrenal incidentaloma.肾上腺偶发瘤或肾上腺嗜铬细胞瘤及文献综述。肾上腺偶发瘤的鉴别诊断。
一例以急性冠状动脉综合征为表现的嗜铬细胞瘤病例。
Cureus. 2024 May 30;16(5):e61389. doi: 10.7759/cureus.61389. eCollection 2024 May.
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A case report on pheochromocytoma mimicking as fulminant myocarditis-a diagnostic challenge.一例误诊为暴发性心肌炎的嗜铬细胞瘤病例报告——诊断挑战
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