Rzeszowska Marzena, Leszcz Agnieszka, Putowski Lechosław, Hałabiś Magdalena, Tkaczuk-Włach Joanna, Kotarski Jan, Polak Grzegorz
Ginekol Pol. 2016;87(9):669-674. doi: 10.5603/GP.2016.0064.
Anti-Müllerian hormone (AMH) is a glycoprotein produced by the granulosa cells of preantral and small antral follicles. AMH concentrations reflect ovarian physiology with high precision, thus serving as a more sensitive marker of the ovarian reserve than the chronological age. This hormone plays a role in the pathogenesis of menstrual disorders and fertility in obesity and polycystic ovary syndrome. The evaluation of AMH may also be useful in the diagnosis or the monitoring therapy of granulosa cells ovarian tumors.
抗苗勒管激素(AMH)是一种由窦前卵泡和小窦卵泡的颗粒细胞产生的糖蛋白。AMH浓度能高精度反映卵巢生理状态,因此作为卵巢储备功能的标志物比实际年龄更敏感。这种激素在肥胖和多囊卵巢综合征的月经紊乱及生育发病机制中起作用。AMH的评估在颗粒细胞卵巢肿瘤的诊断或治疗监测中也可能有用。