Gotmare Swati Shrikant, Tamgadge Avinash, Pereira Treville, Shetty Anusha
Department of Oral and Maxillofacial Pathology and Microbiology, D.Y. Patil University School of Dentistry, Sector 7, Navi Mumbai, Maharashtra, India.
Indian J Dent Res. 2016 Jul-Aug;27(4):441-444. doi: 10.4103/0970-9290.191897.
The keratocystic odontogenic tumor (KCOT), formerly known as odontogenic keratocyst, is a benign developmental odontogenic tumor with many distinguishing clinical and histologic features. Hard tissue deposits, which usually take the form of dystrophic calcifications, cartilaginous tissue, or dentinoid, are uncommon findings in the connective tissue capsule of the KCOT. We report a case of a 33-year-old female with KCOT showing osseous tissue and calcified deposits close to its epithelial lining, which is an extremely rare occurrence. A brief review on the reported prevalence of hard tissue deposits in KCOTs and possible mechanisms that has been implicated in mineralization and bone formation has been discussed.
角化囊性牙源性肿瘤(KCOT),以前称为牙源性角化囊肿,是一种具有许多独特临床和组织学特征的良性发育性牙源性肿瘤。硬组织沉积通常表现为营养不良性钙化、软骨组织或类牙本质,在KCOT的结缔组织包膜中并不常见。我们报告一例33岁女性的KCOT病例,其上皮衬里附近出现骨组织和钙化沉积,这是极为罕见的情况。本文还简要回顾了KCOT中硬组织沉积的报道患病率以及与矿化和骨形成相关的可能机制。