Acosta-Olivo Carlos, Elizondo-Rodriguez Jorge, Lopez-Cavazos Ricardo, Vilchez-Cavazos Felix, Simental-Mendia Mario, Mendoza-Lemus Oscar
J Am Podiatr Med Assoc. 2017 Nov;107(6):490-496. doi: 10.7547/15-125. Epub 2016 Oct 11.
Many treatment options for plantar fasciitis currently exist, some with great success in pain relief. The objective of our study was to compare the use of intralesional steroids with platelet-rich plasma (PRP), using pain scales and functional evaluation, in patients with plantar fasciitis who did not respond to conservative treatment.
A controlled, randomized, blinded clinical assay was performed. Patients were assigned to one of the two groups by selecting a sealed envelope. The steroid treatment group received 8 mg of dexamethasone plus 2 mL of lidocaine as a local anesthetic. The PRP treatment group received 3 mL of PRP activated with 0.45 mL of 10% calcium gluconate. All of the patients were evaluated at the beginning of the study, and at 2, 4, 8, 12, and 16 weeks post-treatment with the Visual Analog Scale (VAS), Foot and Ankle Disability Index (FADI), and American Orthopedic Foot and Ankle Society (AOFAS) scale.
The right foot was the most frequently affected foot (63%). The average age of the patients was 44.8 years (range, 24-61 years). All scales used (VAS, FADI and AOFAS) showed that the difference was not statistically significant between the two groups.
We can conclude that the use of PRP is an effective treatment method for patients with plantar fasciitis who do not respond to conservative treatment because PRP demonstrates an efficacy equal to that of steroids. However, the cost and the time for preparation the PRP are two of the disadvantages of this treatment.
目前存在多种治疗足底筋膜炎的方法,其中一些在缓解疼痛方面取得了显著成效。我们研究的目的是,在对保守治疗无反应的足底筋膜炎患者中,使用疼痛量表和功能评估,比较病灶内注射类固醇与富含血小板血浆(PRP)的疗效。
进行了一项对照、随机、双盲临床试验。通过抽取密封信封将患者分配到两组中的一组。类固醇治疗组接受8毫克地塞米松加2毫升利多卡因作为局部麻醉剂。PRP治疗组接受3毫升用0.45毫升10%葡萄糖酸钙激活的PRP。所有患者在研究开始时以及治疗后2、4、8、12和16周,使用视觉模拟量表(VAS)、足踝残疾指数(FADI)和美国矫形足踝协会(AOFAS)量表进行评估。
右脚是最常受影响的部位(63%)。患者的平均年龄为44.8岁(范围24 - 61岁)。所有使用的量表(VAS、FADI和AOFAS)均显示,两组之间的差异无统计学意义。
我们可以得出结论,对于对保守治疗无反应的足底筋膜炎患者,使用PRP是一种有效的治疗方法,因为PRP显示出与类固醇相当的疗效。然而,PRP的成本和制备时间是这种治疗方法的两个缺点。