Zabeen Bedowra, Nahar Jebun, Tayyeb Samin, Mohsin Fauzia, Nahar Nazmun, Azad Kishwar
Department of Changing Diabetes in Children, Bangladesh Institute of Research and Rehabilitation of Diabetes, Endocrine and Metabolic Disorders, Dhaka, Bangladesh; Department of Paediatrics, Bangladesh Institute of Research and Rehabilitation of Diabetes, Endocrine and Metabolic Disorders, Dhaka, Bangladesh.
Department of Paediatrics, Bangladesh Institute of Research and Rehabilitation of Diabetes, Endocrine and Metabolic Disorders, Dhaka, Bangladesh.
Indian J Endocrinol Metab. 2016 Sep-Oct;20(5):638-642. doi: 10.4103/2230-8210.190544.
Recent data show that the prevalence of diabetes among children and adolescents is increasing in some ethnic groups. The worldwide epidemic of childhood obesity has been accompanied by an increase in the incidence of type 2 diabetes (T2D) in youth.
The aim of this study was to describe the baseline characteristics of children and adolescents diagnosed ≤18 years who had features of T2D and presented at Changing Diabetes in Children, Paediatric Diabetes Clinic at Bangladesh Institute of Research and Rehabilitation of Diabetes, Endocrine, and Metabolic Disorders. All patients who were newly diagnosed and came to the clinic from March 2011 to March 2015 were included.
Among 939 newly registered patients, 77 (8%) had a diagnosis of T2D. The age at diagnosis was 9-10 years in 11 patients (14%), 11-14 years in 46 (60%) and 15-17 years in other 20 patients (26%). Majority of the children had a positive family history of T2D (94%) and 58% were obese. Median fasting insulin (27.9 [17.3-99.3]) was high in 76% patients. Insulin was started initially along with metformin in 40 patients and could be stopped in six patients in 3 months.
Our study reflects that T2D is emerging as a problem in children and adolescents in Bangladesh.
最近的数据显示，某些种族群体中儿童和青少年糖尿病的患病率正在上升。全球儿童肥胖流行伴随着青少年2型糖尿病（T2D）发病率的增加。
本研究的目的是描述在孟加拉国糖尿病、内分泌和代谢疾病研究与康复研究所儿童糖尿病诊所“改变儿童糖尿病”项目中就诊的18岁及以下被诊断为T2D的儿童和青少年的基线特征。纳入了2011年3月至2015年3月期间新诊断并前来诊所就诊的所有患者。
在939名新登记患者中，77名（8%）被诊断为T2D。诊断时年龄为9 - 10岁的有11名患者（14%），11 - 14岁的有46名（60%），15 - 17岁的有20名（26%）。大多数儿童有T2D家族史阳性（94%），58%为肥胖。76%的患者空腹胰岛素中位数（27.9[17.3 - 99.3]）较高。40名患者最初同时开始使用胰岛素和二甲双胍，3个月内6名患者可停用胰岛素。
我们的研究反映出T2D在孟加拉国的儿童和青少年中正在成为一个问题。
