Crespo Iris, Valassi Elena, Webb Susan M
Endocrinology/Medicine Department, Hospital Sant Pau, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBER-ER, Unidad 747), IIB-Sant Pau, ISCIII and Universitat Autònoma de Barcelona (UAB), C/Sant Antoni Maria Claret n.167, 08025, Barcelona, Spain.
Pituitary. 2017 Feb;20(1):185-188. doi: 10.1007/s11102-016-0761-y.
In recent years, health-related quality of life (QoL) has been considered an important outcome for clinical management of acromegaly. Poor QoL has been described in acromegalic patients with active disease as well as after endocrine cure. It is known that acromegaly determines many physical problems and psychological dysfunctions that unavoidably impact on patients' QoL. Moreover, there is evidence that factors, such as radiotherapy or post-treatment GH deficiency also impair QoL in patients diagnosed with acromegaly. Thus, including the assessment of QoL in daily clinical practice has become fundamental to understand the consequences of acromegaly and the impact on the patients' daily life.
近年来，健康相关生活质量（QoL）已被视为肢端肥大症临床管理的一项重要成果。肢端肥大症活动期患者以及内分泌治愈后的患者均存在生活质量不佳的情况。众所周知，肢端肥大症会引发诸多身体问题和心理功能障碍，不可避免地影响患者的生活质量。此外，有证据表明，放疗或治疗后生长激素缺乏等因素也会损害肢端肥大症患者的生活质量。因此，在日常临床实践中纳入生活质量评估已成为了解肢端肥大症后果及其对患者日常生活影响的关键。
