Khurram S, Borhany M, Anwar N, Naseer I, Boota S, Mirza I, Nadeem M, Shamsi T
Department of Blood Bank, National Institute of Blood Disease and Bone Marrow Transplantation, Karachi, Pakistan.
Transfus Med. 2017 Feb;27(1):10-15. doi: 10.1111/tme.12368. Epub 2016 Oct 12.
The aim of the study was to determine the frequency and reasons for donor deferral prior to the blood donation process in our population.
Transfusion is an irreversible event that carries potential risks as well as benefits to the recipient. Therefore, donor selection prior to blood donation is one of the most important steps in ensuring the safety of blood and blood products.
A cross-sectional study was carried out at the blood bank department in our hospital from January 2012 to December 2014. All the blood donors who visited our department in the study period were included in this study.
A total of 25 901 potential donations were recorded during the study period, comprising 24 309 (93·8%) replacement and 1592 (6·2%) voluntary donations. Females accounted for only 222 (0·9%) of potential donations. Deferral occurred in 3156 (12·2%) of attempts; 280 (1·1%) were permanently deferred, while 2876 (11·1%) were temporarily deferred. The most common reason for permanent deferral was a history of hepatitis B infection (n = 147, 4·7% of all deferrals). Major reasons for temporary donor deferral were low levels of haemoglobin (n = 971, 30·76%), low levels of platelets (n = 611, 19·35%) and previous history of jaundice (n = 192, 6·1%).
This study reported a fairly similar pattern of donor deferrals as in other regional studies. Low haemoglobin levels and a history of hepatitis B infection were the most common factors for temporary and permanent donor deferrals, respectively.
本研究旨在确定我国人群在献血过程前被推迟献血的频率及原因。
输血是一种不可逆转的事件，对受血者既有潜在风险也有好处。因此，献血前的献血者筛选是确保血液及血液制品安全的最重要步骤之一。
2012年1月至2014年12月在我院血库进行了一项横断面研究。研究期间到我科室的所有献血者均纳入本研究。
研究期间共记录了25901次潜在献血，其中包括24309次（93.8%）替代献血和1592次（6.2%）自愿献血。女性仅占潜在献血的222次（0.9%）。3156次（12.2%）献血尝试出现推迟；280次（1.1%）被永久推迟，而2876次（11.1%）被暂时推迟。永久推迟的最常见原因是有乙肝感染史（n = 147，占所有推迟的4.7%）。暂时推迟献血的主要原因是血红蛋白水平低（n = 971，30.76%）、血小板水平低（n = 611，19.35%）和既往黄疸病史（n = 192，6.1%）。
本研究报告的献血者推迟模式与其他地区研究相当相似。血红蛋白水平低和乙肝感染史分别是暂时和永久推迟献血的最常见因素。
