Terek A, Sekei J, Getz F
Urol Nefrol (Mosk). 1989 May-Jun(3):69-71.
In 61 patients erectile impotency was treated with papaverine injections into penile spongy body: initially 20-30 mg/day, then followed several days of intermittence, and then the dosages were built up with regard to the optimum time of erection for each person. Dosages higher than 80-100 mg were not advisable because of the evidence of prolonged erections. Recorded in 6 patients (7 times) prolonged erections lasted from 5 to 16 hrs (in 5 cases it was stopped by intracavernous injection of dopamine but in 2 patients cavernotomy was performed). A total of 300 sessions of papaverine intracavernous injections were made in 61 patients before the copulation (out of them 16 patients injected the drug themselves). During the treatment the patients were warned against prolonged erections: when it lasted for more than 4 hrs emergency clinical treatment be required for priapism prevention. It was proved that an adequate dosage of papaverine autoinjections into a spongy body was a simple, safe and effective method to cure erectile impotency, especially in patients with nonadvanced psychoneurological or vasculogenic disorders.
对61例勃起功能障碍患者采用阴茎海绵体内注射罂粟碱进行治疗：初始剂量为每日20 - 30毫克，之后间歇几天，然后根据每个人的最佳勃起时间增加剂量。由于有证据表明会出现阴茎异常勃起时间延长，剂量超过80 - 100毫克并不适宜。6例患者（7次）出现阴茎异常勃起，持续时间为5至16小时（5例通过海绵体内注射多巴胺得以缓解，但有2例患者进行了阴茎海绵体切开术）。在61例患者性交前共进行了300次海绵体内注射罂粟碱治疗（其中16例患者自行注射药物）。治疗期间告知患者警惕阴茎异常勃起：若勃起持续超过4小时，为预防阴茎异常勃起需进行紧急临床治疗。结果证明，对海绵体进行适当剂量的罂粟碱自我注射是一种治疗勃起功能障碍的简单、安全且有效的方法，尤其适用于非晚期精神神经或血管性疾病患者。
