Lund University Diabetes Centre, Department of Clinical Science, Lund University, 205 02 Malmö, Sweden.
Lund University Diabetes Centre, Department of Clinical Science, Lund University, 205 02 Malmö, Sweden; Finnish Institute for Molecular Medicine (FIMM), Helsinki University, 00014 Helsinki, Finland.
Cell Metab. 2016 Oct 11;24(4):523-524. doi: 10.1016/j.cmet.2016.09.012.
RNA sequencing of human pancreatic islets has provided important insights into the islet transcriptome but little information on the specific cells. In this issue, Segerstolpe et al. (2016) and Xin et al. (2016b) report on the transcriptome of single pancreatic cells from non-diabetic and type 2 diabetic donors.
人类胰岛的 RNA 测序为胰岛转录组提供了重要的见解,但对特定细胞的信息了解甚少。在本期中,Segerstolpe 等人(2016 年)和 Xin 等人(2016b)报道了来自非糖尿病和 2 型糖尿病供体的单个胰腺细胞的转录组。